QRICH1 and CEACAM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		QRICH1	CEACAM6
Description		glutamine rich 1	CEA cell adhesion molecule 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane
	Molecular Function	DNA Binding Protein Binding	Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress PERK-mediated Unfolded Protein Response Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Integrated Stress Response Signaling	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis
Pathways			Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) General factor of neuroticism ( 30867560) Inflammatory bowel disease ( 28067908) Refractive error ( 32231278) Resting heart rate ( 27798624) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172)	Serum carcinoembryonic antigen levels ( 31666285)
Interacting Genes		58 interacting genes: ACTL9 ARID5A ATF7IP ATXN1 BICRAL C15orf65 C19orf54 CEACAM6 CRX CYSRT1 DNAAF6 ELP6 FAM166B FHL2 FHL3 FHL5 GMCL1 HIVEP1 HSFY1 HSPB8 IP6K2 KHDC4 KIAA1143 KLHDC7B LASP1 LBX1 LHX3 LHX4 LMO3 LMO4 MEOX1 MYH7B NFIX NFYA NLK P4HTM PAX6 POGZ POU6F2 PRKAR1B PUF60 RBM17 SELENOV SEPHS1 SIAH1 SMAP1 SP2 SRARP TEKT5 TMA7 TOX4 TRAF1 TRAF2 USP54 YPEL3 ZDHHC17 ZMAT1 ZYX	32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76
Entrez ID		54870	4680
HPRD ID		13372	01233
Ensembl ID		ENSG00000198218	ENSG00000086548
Uniprot IDs		A1L3Z9 Q2TAL8	P40199
PDB IDs			4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?
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