APTX and CNTROB

Number of citations of the paper that reports this interaction (PubMedID 16713569)
337

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APTX	CNTROB
Description		aprataxin	centrobin, centriole duplication and spindle assembly protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm	Centrosome Centriole Cytosol
	Molecular Function	Chromatin Binding Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Double-stranded RNA Binding Protein Binding Phosphoglycolate Phosphatase Activity Mismatched DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Metal Ion Binding Protein N-terminus Binding Phosphoprotein Binding DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Single Strand Break Repair DNA Ligation Double-strand Break Repair Cellular Response To DNA Damage Stimulus Dephosphorylation Regulation Of Protein Stability Response To Hydrogen Peroxide Nucleic Acid Phosphodiester Bond Hydrolysis	Centriole Replication Centrosome Separation Regulation Of Cilium Assembly Mitotic Cytokinetic Process
Pathways
Drugs
Diseases
GWAS		Height ( 28552196) Menopause (age at onset) ( 26414677)	Refractive error ( 32231278)
Interacting Genes		18 interacting genes: CALCOCO1 CEP350 CNTROB FLAD1 HIVEP1 MAPKBP1 MBP PARP1 PICK1 PNMA1 PNMA3 SYT17 TP53 TRIM37 TSPYL2 XRCC1 XRCC4 ZNF639	23 interacting genes: APTX COASY CWF19L2 DAPK1 DUSP29 ELOA EPM2AIP1 GSK3A HPCAL4 KRBA2 LYST MCRS1 PELI1 PNKP RAD23A RSPH14 SMARCA2 SYT6 TCEA2 TSC1 TSHZ2 TTC23 USP43
Entrez ID		54840	116840
HPRD ID		05892	13991
Ensembl ID		ENSG00000137074	ENSG00000170037
Uniprot IDs		Q7Z2E3	Q8N137
PDB IDs		3KT9 4NDF 4NDG 4NDH 4NDI 6CVO 6CVP 6CVQ 6CVR 6CVS 6CVT
Enriched GO Terms of Interacting Partners?
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