OTUD4 and DNAAF5

		OTUD4	DNAAF5
Description		OTU deubiquitinase 4	dynein axonemal assembly factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Cytoplasm Motile Cilium Dynein Axonemal Particle
	Molecular Function	RNA Binding Thiol-dependent Deubiquitinase Protein Binding Molecular Adaptor Activity Lys63-specific Deubiquitinase Activity	Dynein Intermediate Chain Binding
	Biological Process	Protein Deubiquitination Negative Regulation Of Toll-like Receptor Signaling Pathway Innate Immune Response Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of DNA Demethylation Regulation Of Protein K48-linked Deubiquitination Negative Regulation Of Interleukin-1-mediated Signaling Pathway	Cilium Movement Outer Dynein Arm Assembly Inner Dynein Arm Assembly
Pathways
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172 25673412) Lung function (FEV1) ( 30061609) Malaria ( 31844061) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 31628463) Red blood cell count ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 27863252) Subcortical volume (MOSTest) ( 32665545)	Cerebrospinal P-tau181p levels ( 28247064) Initial pursuit acceleration ( 29064472) Retinitis pigmentosa ( 33514863)
Interacting Genes		13 interacting genes: ALKBH3 DNAAF5 EXOSC8 MAVS REL RPS6KA2 STAT1 TCF4 TEC UBC USP7 VDR ZNF655	8 interacting genes: ADAP1 BUD23 FEZ1 GET4 INTS1 MMP16 OTUD4 ZBTB16
Entrez ID		54726	54919
HPRD ID		11033	07903
Ensembl ID		ENSG00000164164	ENSG00000164818
Uniprot IDs		Q01804	B3KPE2 Q86Y56
PDB IDs
Enriched GO Terms of Interacting Partners?
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