RBFOX1 and MPG

		RBFOX1	MPG
Description		RNA binding fox-1 homolog 1	N-methylpurine DNA glycosylase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network Cytoplasmic Stress Granule Nuclear Stress Granule	Nucleoplasm Cytosol Mitochondrial Nucleoid
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Protein C-terminus Binding	Damaged DNA Binding Alkylbase DNA N-glycosylase Activity Protein Binding DNA-3-methyladenine Glycosylase Activity DNA N-glycosylase Activity DNA-7-methylguanine Glycosylase Activity DNA-7-methyladenine Glycosylase Activity DNA-3-methylguanine Glycosylase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing RNA Transport Neuromuscular Process Controlling Balance Regulation Of Skeletal Muscle Cell Differentiation	Base-excision Repair DNA Dealkylation Involved In DNA Repair Depurination
Pathways		MECP2 regulates transcription factors	Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Displacement of DNA glycosylase by APEX1
Drugs			Cisplatin Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Adult body size ( 32376654) Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686) Age at first sexual intercourse ( 34211149) Albumin-globulin ratio ( 29403010) Allergic rhinitis ( 25085501) Alzheimer's disease ( 33074286) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Bitter alcoholic beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Body mass index ( 28892062 25673413) Brain glucose metabolism (fluorodeoxyglucose uptake) ( 30596066) Brain volume in infants (cerebrospinal fluid) ( 28763065) Cataracts ( 34127677) Cerebellum white matter volume ( 31530798) Chronotype ( 30696823) Cocaine dependence ( 31212010) Cognitive decline rate in late mild cognitive impairment ( 26252872) Depression ( 33859377 29700475) Evening vs. morning chronotype (sMEQ score) ( 32579418) Extraversion ( 27918536) Feeling worry ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Glaucoma ( 25027321) HDL cholesterol levels in HIV infection ( 33109212) High myopia ( 31816047) Hydrolysed wheat protein allergy ( 31301374) Hyperopia ( 25233373) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) joint destruction in rheumatoid arthritis (rapid vs slow) ( 33585033) Major depressive disorder ( 27479909 29728651) Mental health study participation (completed survey) ( 31263887) Metabolite levels ( 31628463) Myopia ( 27182965 25233373) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Neuroticism ( 29255261) Nickel levels ( 26025379) Nontraumatic osteonecrosis of the femoral head ( 32701715) Obesity (extreme) ( 31852448) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Photic sneeze reflex ( 27182965) Pit-and-Fissure caries ( 24556642) Refractive astigmatism ( 30306274) Refractive error ( 23396134 32231278 23474815) Renal cell carcinoma ( 31231134) Rheumatoid arthritis ( 30423114) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systemising ( 31508503) Systolic blood pressure ( 30224653) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) Triglyceride levels ( 34074324) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 30130595) Worry too long after an embarrassing experience ( 29500382)	Blood protein levels ( 30072576) Glioblastoma ( 28346443) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell traits ( 23446634)
Interacting Genes		53 interacting genes: AGR2 AHCY ALG13 ARID5A ATN1 ATXN1 ATXN1L ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HCFC1R1 HNRNPF HSFX1 HSFY1 HYPK KIFAP3 LASP1 LZTS2 MAGED1 MAOB MPG NOC2L NUMBL P4HA3 PCBP4 POGZ PRR20A PRRC2A PSMF1 QKI RBFOX2 RBFOX3 RBM24 RBM47 RBPMS RBPMS2 RHOXF2 SIRPB1 SNRPN STRBP TEX37 TNIP1 TOLLIP UBL3 VENTX	14 interacting genes: APP CRK EP300 ESR1 FBXO7 GPR182 HSD17B14 MLH1 RAD23A RAD23B RBFOX1 RXRA TERF2IP THRB
Entrez ID		54715	4350
HPRD ID		16091	06766
Ensembl ID		ENSG00000078328	ENSG00000103152
Uniprot IDs		A0A6Q8PH77 B7Z1U7 Q59HD3 Q9NWB1 X5D7T5 X5DNY3 X5DP44	P29372 Q1W6H1
PDB IDs		2ERR 2N82 4ZKA	1BNK 1EWN 1F4R 1F6O 3QI5 3UBY
Enriched GO Terms of Interacting Partners?
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