EPB41L4B and HSP90B1

		EPB41L4B	HSP90B1
Description		erythrocyte membrane protein band 4.1 like 4B	heat shock protein 90 beta family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Apical Part Of Cell	Extracellular Region Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Focal Adhesion Membrane Midbody Protein-containing Complex Sarcoplasmic Reticulum Lumen Endoplasmic Reticulum Chaperone Complex Melanosome Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome Endocytic Vesicle Lumen
	Molecular Function	Structural Constituent Of Cytoskeleton Cytoskeletal Protein Binding	RNA Binding Calcium Ion Binding Protein Binding ATP Binding Protein Phosphatase Binding Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding
	Biological Process	Positive Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Actomyosin Structure Organization Wound Healing Positive Regulation Of Cell Adhesion Positive Regulation Of Keratinocyte Migration	Response To Hypoxia Protein Folding Protein Transport Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Actin Rod Assembly Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Sequestering Of Calcium Ion Cellular Response To ATP
Pathways			Trafficking and processing of endosomal TLR Scavenging by Class A Receptors Scavenging by Class A Receptors ATF6 (ATF6-alpha) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Interleukin-4 and Interleukin-13 signaling Post-translational protein phosphorylation
Drugs			Rifabutin 2-Chlorodideoxyadenosine Geldanamycin Diglyme N-Ethyl-5'-Carboxamido Adenosine Radicicol METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE Copper
Diseases
GWAS		Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301) Body mass index ( 28892062 25673413) Degraded stimulus continuous performance test score ( 31596458) High density lipoprotein cholesterol levels ( 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Low vWF levels ( 26486471) Staphylococcus aureus nasal carriage (persistent) ( 26569114) Umami taste perception in obesity with metabolic syndrome ( 31005965)	Blood protein levels ( 29875488) Metabolite levels ( 23823483) Soluble VCAM-1 levels ( 31217265)
Interacting Genes		3 interacting genes: HSP90B1 LAMC3 SRPK2	39 interacting genes: APOB ASGR1 BIRC2 CACYBP CAMLG CCT2 CSNK2A1 CSNK2A2 CYSLTR2 EGFR EPB41L4B ERBB2 ESR1 FANCC GPR37 HSPA9 LINC01554 LRP1 MAPK6 MDM2 MMP17 MTTP NKX3-1 OGT OS9 POLR2E PTEN PTPN11 RXFP3 SGTB SIRPA SUPT6H TG TLR1 TLR2 TLR4 TP53 TXNDC11 UBASH3A
Entrez ID		54566	7184
HPRD ID		09940	01860
Ensembl ID		ENSG00000095203	ENSG00000166598
Uniprot IDs		Q59GC2 Q9H329 Q9NSG9 Q9NX84	P14625 V9HWP2
PDB IDs			4NH9
Enriched GO Terms of Interacting Partners?
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