CRCT1 and TGM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CRCT1	TGM1
Description		cysteine rich C-terminal 1	transglutaminase 1
Image		No pdb structure
GO Annotations	Cellular Component		Cornified Envelope Cytosol Plasma Membrane Membrane Intrinsic Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process		Cellular Protein Modification Process Positive Regulation Of Keratinocyte Proliferation Peptide Cross-linking Keratinocyte Differentiation Keratinization Cell Envelope Organization Positive Regulation Of Cell Cycle
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 21804549 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 26482879) Obesity-related traits ( 23251661) Plantar warts ( 28928442)
Interacting Genes		55 interacting genes: AGTRAP ALPP APLP1 CEP126 CHD3 CYP21A2 CYSRT1 EEF1A1 GRN IGSF21 KRTAP1-3 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1C LCE1F LCE2B LCE2C LCE4A LRIF1 MACO1 MEOX2 NOTCH2NLA NUP62 OIT3 PLSCR4 PTN RGS17 RGS20 SDCBP2 SLC39A7 TGM1 TLE1 TRIM55 TRIM63 VIM VWC2L	34 interacting genes: ACADL ALPP C1QTNF1 CNNM3 CRCT1 CXCL16 DOCK2 GSTP1 HSPB1 IFI30 IGSF8 ITGB4 JOSD1 KRTAP4-12 KRTAP5-9 LCE1B LCE1E LCE3A LCE4A MDK MYPOP NECTIN2 NUBP2 PLAAT4 RIN3 SCARF1 SEMG1 SEMG2 SNCA SULT4A1 TACC2 TRAPPC14 VASN VSTM4
Entrez ID		54544	7051
HPRD ID		16635	01824
Ensembl ID		ENSG00000169509	ENSG00000092295
Uniprot IDs		Q9UGL9	P22735
PDB IDs			2XZZ
Enriched GO Terms of Interacting Partners?
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