ROBO4 and ENAH

Number of citations of the paper that reports this interaction (PubMedID 12941633)
120

Data Source:
HPRD (in vitro)

		ROBO4	ENAH
Description		roundabout guidance receptor 4	ENAH actin regulator
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Axon Extracellular Exosome	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium Cell Junction Filopodium Synapse
	Molecular Function	Protein Binding Signaling Receptor Activity Cell-cell Adhesion Mediator Activity	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding WW Domain Binding
	Biological Process	Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Regulation Of Cell Migration Establishment Of Endothelial Barrier Dendrite Self-avoidance	Axon Guidance Actin Polymerization Or Depolymerization Actin Polymerization-dependent Cell Motility
Pathways			Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors
Drugs
Diseases
GWAS		Breast cancer (survival) ( 25890600) Venous thromboembolism ( 32232851)	Delirium ( 29631748) Depression in smokers ( 30219690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Neuroticism ( 27067015) Obesity-related traits ( 23251661)
Interacting Genes		5 interacting genes: CEP19 ENAH PPARG RXRA THRB	28 interacting genes: ABI1 ABI2 ABI3 ABL1 APBB1 BAIAP2 DNAH14 DNMBP EVL FAT1 FYB1 GPHN HMGB1 KLHDC3 MAPK1 PFN1 PRPF40A RAC1 RAD51 ROBO4 SPTA1 TERF2IP TES VASP WAS XIRP1 YAP1 ZYX
Entrez ID		54538	55740
HPRD ID		09604	12360
Ensembl ID		ENSG00000154133	ENSG00000154380
Uniprot IDs		B4DYV8 Q8WZ75	A0A4D6J698 Q8N8S7
PDB IDs			2HO2 2IYB 2XQN 4MY6 5N91 5N9C 5N9P 5NAJ 5NBF 5NBX 5NC2 5NC7 5NCF 5NCG 5NCP 5ND0 5NDU 5NEG 6RCF 6RCJ 6RD2 6XVT 6XXR 7A5M 7AKI
Enriched GO Terms of Interacting Partners?
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