ADAMTSL4 and CXCL16

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	CXCL16
Description		ADAMTS like 4	C-X-C motif chemokine ligand 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Interstitial Matrix Endoplasmic Reticulum Lumen Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protease Binding Protein Binding	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Chemokine Activity
	Biological Process	Epithelial Cell Development Apoptotic Process Extracellular Matrix Organization Positive Regulation Of Apoptotic Process	Receptor-mediated Endocytosis Chemotaxis Signal Transduction T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Interferon-gamma Response To Tumor Necrosis Factor
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Asthma ( 32296059) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Migraine ( 27322543) Refractive error ( 32231278) Rhegmatogenous retinal detachment ( 23585552) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		211 interacting genes: ADAM12 ADAMTSL5 ALPP AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 ATG9A BAG4 BANF2 BOLA2 BOLA2B BRME1 CATSPER1 CBX3 CCDC26 CFAP206 CHCHD2 CHERP CHIC2 CHRD CHRNG CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 CYSRT1 DGCR6 DGCR6L DIP2A DLK2 DNPEP DSCR8 EFEMP2 EIF4E2 EPDR1 ERCC3 EXOSC5 FAH FAM124B FARS2 FBLN1 FBXO17 FBXW5 FHL3 FKBP1B FLNA FRS3 FXR1 GATA2 GIP GLRX3 GLYCTK GMCL2 GNE GNG13 GNMT GOLGA8EP GSTP1 GUCD1 HEXIM2 HGF HNRNPLL HOXA1 HOXC8 HSD3B7 INS IP6K1 ITGB2 ITGB4 JOSD1 KCTD7 KCTD9 KIF1A KLHL38 KRTAP1-1 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP19-2 KRTAP21-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 LCE1A LCE1B LCE1C LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LGALS14 LHX4 LINC00671 LMO1 LMO2 LMO4 LNX1 LONRF1 LRFN4 LRRC29 MAGOHB MAPKBP1 MGAT5B MID2 MKRN3 MORN3 MVP MYLIP MYO15B NATD1 NBPF19 NEK8 NFKBID NMUR2 NOTCH2NLA NR4A3 NTAQ1 NTF4 NTN4 NUFIP2 OLFM3 OTX1 PCSK5 PID1 PIN1 PKN1 PLEKHO1 PLSCR1 PLSCR4 POLD1 POLR1C POU4F2 PRKAB2 PRR19 PTGER3 PTPMT1 QPRT R3HDM2 RAB2B RCHY1 RGL2 RHOJ RPS19BP1 RUNX1T1 SALL2 SCNM1 SHFL SLC13A5 SLC23A1 SLC6A20 SLIT1 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY1 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TFAP2D TGFB1 THAP6 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIM55 TRIM63 TRIP6 TSSK3 TUBGCP4 USP21 VASN VENTX VWC2 ZFHX2 ZNF330 ZNF414 ZNF417 ZNF587	64 interacting genes: ADAMTSL4 APP AQP2 AQP6 AQP9 ARL13B ATP6V0E1 BIK CARD10 CCDC70 CD53 CERS4 CLDN7 CREB3L1 CXCR6 CYSRT1 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GORAB GPR42 HHATL HOXA1 KASH5 KIR2DL3 KRT31 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP5-9 LHFPL5 LMNA MDFI MFF MTUS2 MUC1 NBPF19 NEMP1 NOTCH2NLA PEX12 SAR1A SLC16A2 SLC18A1 SLC39A1 SPN SSMEM1 STX1A TAB1 TGM1 TLCD4 TMEM139 TMEM14B TMEM237 TMEM239 TMEM35A TMX2 TSPAN12
Entrez ID		54507	58191
HPRD ID		18237	16103
Ensembl ID		ENSG00000143382	ENSG00000161921
Uniprot IDs		A0A669KBE7 B7ZMJ3 Q6UY14 Q9UFG7	Q9H2A7
PDB IDs
Enriched GO Terms of Interacting Partners?
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