PRMT7 and H3-5

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (two hybrid)

		PRMT7	H3-5
Description		protein arginine methyltransferase 7	H3.5 histone
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytosol	Nucleosome Euchromatin Barr Body Nucleus
	Molecular Function	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)	Protein Binding Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	Spliceosomal SnRNP Assembly Regulation Of Gene Expression By Genetic Imprinting Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation	Osteoblast Differentiation Nucleus Organization Spermatid Development Single Fertilization Embryo Implantation Cell Population Proliferation Male Gonad Development Positive Regulation Of Cell Growth Pericentric Heterochromatin Assembly Subtelomeric Heterochromatin Assembly Multicellular Organism Growth Muscle Cell Differentiation Oogenesis Regulation Of Centromere Complex Assembly Negative Regulation Of Chromosome Condensation
Pathways		RMTs methylate histone arginines
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 33730874) Birth weight ( 31043758) Body mass index ( 28892062 25673413) Body shape index ( 34021172) Magnesium levels ( 20700443) Offspring birth weight ( 31043758) Refractive error ( 32231278) Schizophrenia ( 31579629) Serum metabolite levels ( 23093944) Weight ( 28552196)
Interacting Genes		14 interacting genes: CTCFL DIO3 EIF2S1 H2AC20 H3-5 H3C1 H4C1 MNDA NFKBID POT1 SNRPB TRIO ZBTB24 ZNF438	15 interacting genes: DAXX DNAJC9 FBLIM1 KAT6A KDM1A KDM4B NASP NSD3 PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1
Entrez ID		54496	440093
HPRD ID		15174	18443
Ensembl ID		ENSG00000132600	ENSG00000188375
Uniprot IDs		A0A024R726 Q9NVM4	Q6NXT2
PDB IDs			2PUY 3KV4 4Z5T 5BWN 5BWO 5F6K 5I3L 6OI3
Enriched GO Terms of Interacting Partners?
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