RIPK4 and TRAF7

Number of citations of the paper that reports this interaction (PubMedID 21903422)
143

Data Source:
BioGRID (affinity chromatography technology, pull down)

		RIPK4	TRAF7
Description		receptor interacting serine/threonine kinase 4	TNF receptor associated factor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane	Ubiquitin Ligase Complex Nucleolus Plasma Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding ATP Binding Protein Serine Kinase Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding
	Biological Process	Morphogenesis Of An Epithelium Protein Phosphorylation Positive Regulation Of NF-kappaB Transcription Factor Activity	Ribosomal Large Subunit Assembly Apoptotic Process Notch Signaling Pathway Protein Ubiquitination Positive Regulation Of MAPK Cascade Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Diastolic blood pressure ( 30578418) Height ( 28552196) Liver enzyme levels (alkaline phosphatase) ( 33972514) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		10 interacting genes: BIRC2 BIRC3 GPSM3 PRKCB PRKCD RHOA SPAG8 TRAF7 VWC2L XIAP	18 interacting genes: BTBD1 CDC42 CYLD HAGHL HDGF MAP3K3 NUDT16L1 OGT PBXIP1 PPIC RIPK4 TRAF6 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2L3 UBE2L6
Entrez ID		54101	84231
HPRD ID		10419	06977
Ensembl ID		ENSG00000183421	ENSG00000131653
Uniprot IDs		Q96T11 Q9H4D1	B3KQY7 Q6Q0C0
PDB IDs
Enriched GO Terms of Interacting Partners?
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