MIS18A and CCDC115

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIS18A	CCDC115
Description		MIS18 kinetochore protein A	coiled-coil domain containing 115
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytosol	Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vacuolar Proton-transporting V-type ATPase Complex COPI-coated Vesicle Extrinsic Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Unfolded Protein Binding
	Biological Process	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of DNA Methylation Cell Division	Cellular Iron Ion Homeostasis Lysosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	RHOA GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CCDC115 CNGA3 DMAP1 FNDC11 GCSH GLYCTK HJURP IFT20 MAFIP MBIP NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA ZNF471 ZNF655	10 interacting genes: ABI2 ALOX15B APP CSNK2B MIS18A NTAQ1 PLK1 PRKCZ RARS1 TK1
Entrez ID		54069	84317
HPRD ID		10749	14428
Ensembl ID		ENSG00000159055	ENSG00000136710
Uniprot IDs		Q9NYP9	A1QKJ6 B8ZZ99 Q96NT0
PDB IDs
Enriched GO Terms of Interacting Partners?
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