PLIN1 and LIPE

Number of citations of the paper that reports this interaction (PubMedID 17189257)
116

Data Source:
BioGRID (fluorescent resonance energy transfer, protein complementation assay, fluorescent resonance energy transfer, affinity chromatography technology)

		PLIN1	LIPE
Description		perilipin 1	lipase E, hormone sensitive type
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol	Lipid Droplet Cytosol Caveola Membrane
	Molecular Function	Protein Binding Lipid Binding	Sterol Esterase Activity Triglyceride Lipase Activity Protein Binding Hormone-sensitive Lipase Activity Acylglycerol Lipase Activity All-trans-retinyl-palmitate Hydrolase, All-trans-retinol Forming Activity Retinyl-palmitate Esterase Activity 1,3-diacylglycerol Acylhydrolase Activity 1,2-diacylglycerol Acylhydrolase Activity
	Biological Process	Lipid Metabolic Process Lipid Catabolic Process Cellular Response To Cold	Protein Phosphorylation Cholesterol Metabolic Process Lipid Catabolic Process Triglyceride Catabolic Process Retinol Metabolic Process Diacylglycerol Catabolic Process Ether Lipid Metabolic Process
Pathways		Triglyceride catabolism Transcriptional regulation of white adipocyte differentiation NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose	Triglyceride catabolism
Drugs
Diseases
GWAS		HDL cholesterol ( 30275531)
Interacting Genes		4 interacting genes: ABHD5 BSCL2 LIPE PRKACA	11 interacting genes: FABP4 KATNA1 MAPK1 MAPK3 MTNR1A NSFL1C PLIN1 PLIN5 PRKACA STAR TSGA10IP
Entrez ID		5346	3991
HPRD ID		01364	01062
Ensembl ID		ENSG00000166819	ENSG00000079435
Uniprot IDs		O60240	A8K8W7 Q05469
PDB IDs
Enriched GO Terms of Interacting Partners?
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