ATP6V1E1 and ALDOA

Number of citations of the paper that reports this interaction (PubMedID 11399750)
61

Data Source:
HPRD (in vitro, two hybrid)

		ATP6V1E1	ALDOA
Description		ATPase H+ transporting V1 subunit E1	aldolase, fructose-bisphosphate A
Image
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Extracellular Exosome	Extracellular Region Extracellular Space Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Secretory Granule Lumen Sperm Head Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Hydrolase Activity Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	RNA Binding Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Cadherin Binding Fructose Binding
	Biological Process	Regulation Of Macroautophagy Proton Transmembrane Transport	Fructose Metabolic Process Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Binding Of Sperm To Zona Pellucida Regulation Of Cell Shape Fructose 1,6-bisphosphate Metabolic Process Muscle Cell Cellular Homeostasis Protein Homotetramerization
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs		Tiludronic acid	Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Cataracts ( 34127677) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Monocyte count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		14 interacting genes: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H HSPB2 MESD SLC9A3R1 SOS1 TRAF6 XRCC6	35 interacting genes: ADRB2 ALDOB ATP6V1E1 BCAT2 CACNA1A CYTH2 DYNLL1 EGFR ENO1 ENO3 ERBB2 ERBB3 ERBB4 FANCA GALNT6 GPD2 HSD17B10 HSPB2 IFNA4 LINC01554 MLH1 MYOC OGT PCNA PIAS4 PLD2 SHANK3 SLC22A1 SRPK2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1
Entrez ID		529	226
HPRD ID		00163	00070
Ensembl ID		ENSG00000131100	ENSG00000149925
Uniprot IDs		P36543 Q53Y06	P04075 V9HWN7
PDB IDs		6WLZ 6WM2 6WM3 6WM4	1ALD 2ALD 4ALD 5KY6
Enriched GO Terms of Interacting Partners?
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