ACP1 and OS9

		ACP1	OS9
Description		acid phosphatase 1	OS9 endoplasmic reticulum lectin
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Sarcolemma Extracellular Exosome	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane
	Molecular Function	Acid Phosphatase Activity Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Protease Binding Protein Binding Carbohydrate Binding
	Biological Process	Peptidyl-tyrosine Dephosphorylation	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs		Adenine 4-Nitrophenyl Phosphate
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Large artery stroke ( 28265093) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Refractive error ( 32231278)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)
Interacting Genes		17 interacting genes: BARD1 CTNNB1 EPHA2 EPHB1 EPHB2 ERBB2 FABP4 FNBP1L FYN INSR KDR LCK MRPL20 OS9 SFMBT1 SPTAN1 ZAP70	28 interacting genes: ACP1 ACVR1B CPNE6 CREB3 DCSTAMP DYSF EGLN1 EGLN3 EIF6 FAIM2 FOXM1 GLS2 HIF1A HSP90B1 LINC00839 MEP1B P3H3 PGD PTH RBX1 SCN8A SLC22A1 SMAD2 SNRPD2 SREBF2 TRPV4 UVRAG ZNF512B
Entrez ID		52	10956
HPRD ID		08881	17804
Ensembl ID		ENSG00000143727	ENSG00000135506
Uniprot IDs		A0A140VK37 P24666 Q59EH3	Q13438
PDB IDs		1XWW 3N8I 4Z99 4Z9A 4Z9B 5JNR 5JNS 5JNT 5KQG 5KQL 5KQM 5KQP 5PNT 6Y2V 6Y2W	3AIH
Enriched GO Terms of Interacting Partners?
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