ZNF581 and APOBEC3C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF581	APOBEC3C
Description		zinc finger protein 581	apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	P-body Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Cytidine Deamination Negative Regulation Of Transposition Cytidine To Uridine Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways			mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS			Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		96 interacting genes: AP2M1 APOBEC3C APP ASB13 ATG9A BANP BOLA2 BOLA2B CALCOCO2 CARD10 CBY2 CCDC136 CCNDBP1 CHURC1 CNFN CYSRT1 DAZAP2 DOCK8 DVL2 DVL3 EFEMP2 ENKD1 ETFDH FAM90A1 FANCL FHL5 FSD2 GOLGA2 GOLGA6L9 GOPC GPSM3 HMBOX1 HNRNPC HNRNPF HSF2BP IKZF1 IL16 KDM1A KHDRBS2 KRT27 KRT34 KRT40 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP6-2 LNX1 LNX2 LZTS2 MDFI MGAT5B MTUS2 NAT14 NBPF19 NID2 NOTCH2NLA NUDT22 PDE4DIP PLAGL2 PLEKHF2 PLSCR1 PNMA1 POU2AF1 PRKAB2 RBPMS RIMBP3C RSKR SDCBP2 SERTAD2 SMARCC1 SOX5 SPAG8 SPG21 SUV39H1 TEKT4 TMCC2 TRAF1 TRAF4 TRIM23 TRIM27 TRIM55 TRIM63 TRIP6 WWOX ZNF765 ZNF792 ZRANB1	19 interacting genes: CHTOP FBXO7 HHEX HNRNPK PRR3 RBMX RBMY1A1 RBMY1F RBMY1J SHBG SRPK2 STK4 SUN2 TRAF3 TRIB3 ZNF250 ZNF408 ZNF48 ZNF581
Entrez ID		51545	27350
HPRD ID		15858	09671
Ensembl ID		ENSG00000171425	ENSG00000244509
Uniprot IDs		Q9P0T4	Q9NRW3
PDB IDs			3VM8 3VOW
Enriched GO Terms of Interacting Partners?
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