PDE9A and KRTAP12-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PDE9A	KRTAP12-2
Description		phosphodiesterase 9A	keratin associated protein 12-2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Ruffle Membrane Sarcolemma Perikaryon Perinuclear Region Of Cytoplasm	Cytosol Keratin Filament
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy CGMP-mediated Signaling CGMP Metabolic Process CGMP Catabolic Process
Pathways		cGMP effects	Keratinization
Drugs		Caffeine gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine 3-isobutyl-1-methyl-7H-xanthine Trapidil
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Perceived unattractiveness to mosquitoes ( 28199695)
Interacting Genes		41 interacting genes: BAG3 CDC37 CLK1 CRY2 CYSRT1 ERG FXR1 FXR2 GORASP2 IQCB1 KANK2 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP4-2 KRTAP5-9 KRTAP9-2 LAGE3 LINC02913 LMO2 MX1 NAA38 NFIL3 NOTCH2NLA PCNT PHYHIPL PRPF18 SDCBP SULT1E1 TFAP4 TRIM32 TRPV6 UBD UTP23 WDR5	125 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1C LCE1F LCE2A LCE2B LCE4A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPRED2 SPRY1 SRSF8 TCEA2 TEX37 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1
Entrez ID		5152	353323
HPRD ID		09115	11198
Ensembl ID		ENSG00000160191	ENSG00000221864
Uniprot IDs		A0A0S2Z475 A0A0S2Z4A3 A0A0S2Z4T6 O76083	P59991
PDB IDs		2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6 4Y86 4Y87 4Y8C 6A3N 6LZZ
Enriched GO Terms of Interacting Partners?
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