GTSE1 and KIFAP3

Number of citations of the paper that reports this interaction (PubMedID 30217970)
5

Data Source:
BioGRID (two hybrid)

		GTSE1	KIFAP3
Description		G2 and S-phase expressed 1	kinesin associated protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane	Condensed Nuclear Chromosome Endoplasmic Reticulum Golgi Apparatus Centrosome Cytosol Spindle Microtubule Cilium Axoneme Microtubule Cytoskeleton Kinesin II Complex Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Periciliary Membrane Compartment
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Protein Binding Kinesin Binding Protein Phosphatase Binding Intraciliary Transport Particle B Binding
	Biological Process	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Microtubule-based Process	Microtubule-based Process Microtubule-based Movement Signal Transduction Protein Localization Negative Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Cilium Organization Positive Regulation Of Calcium-dependent Cell-cell Adhesion Protein-containing Complex Assembly Plus-end-directed Vesicle Transport Along Microtubule
Pathways		G2/M Checkpoints The role of GTSE1 in G2/M progression after G2 checkpoint	Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS			Acute anterior uveitis in ankylosing spondylitis ( 32492107) Adverse response to drug ( 30420678) Amyotrophic lateral sclerosis ( 19451621) Atrial fibrillation ( 28416818) L-selectin levels ( 25576479) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: AKAP9 CASK FXR2 HNRNPD KIFAP3 MAPRE1 MAPRE2 MAPRE3 NIN RBM10	34 interacting genes: APC AR C19orf44 CCSER2 DHX37 DISC1 GTSE1 HOXB5 KANK2 KIF3B MAP3K10 MAP3K11 MARK2 MEST MINK1 MOS MYPOP NAA10 NAA11 NAV1 NCF2 NIPSNAP3A NUDT21 PARD6G PEX19 PRNP RAP1GDS1 RBFOX1 RBM14 RPGR RTP5 SMC3 SRC TOR1AIP1
Entrez ID		51512	22920
HPRD ID		09593	03499
Ensembl ID		ENSG00000075218	ENSG00000075945
Uniprot IDs		Q9NYZ3	Q92845
PDB IDs		6QNN 6QNP
Enriched GO Terms of Interacting Partners?
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