NELFCD and GSTM4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NELFCD	GSTM4
Description		negative elongation factor complex member C/D	glutathione S-transferase mu 4
Image
GO Annotations	Cellular Component	Nucleoplasm Membrane NELF Complex	Cytoplasm Cytosol Intercellular Bridge
	Molecular Function	RNA Binding Protein Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Protein Binding Enzyme Binding Protein Homodimerization Activity Glutathione Binding
	Biological Process	Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter	Glutathione Metabolic Process Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Long-chain Fatty Acid Biosynthetic Process
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation	Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Drugs			Glutathione Glutathione sulfonic acid S-octylglutathione Glutathione disulfide gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane S-Hexylglutathione
Diseases
GWAS		Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 27863252)	Alcohol dependence ( 33290381) Seasonality and depression ( 30217971)
Interacting Genes		22 interacting genes: AAMP AR ARAF ARPC4 CACNA1A CD40 CDSN DNAJA1 ENDOV EPRS1 FRMD5 GSTM4 HDAC11 MTA1 NELFA OGT PRMT5 SERF2 SMAD4 TXK UBE3A ZNF638	11 interacting genes: APLP1 GSTM3 GSTM5 IGSF21 LRIF1 MED31 NELFCD TLE1 TP53 UNC119 ZBTB16
Entrez ID		51497	2948
HPRD ID		16096	00706
Ensembl ID		ENSG00000101158	ENSG00000168765
Uniprot IDs		H0UI80 Q8IXH7	A0A140VKE3 Q03013
PDB IDs		5L3X 6GML	4GTU
Enriched GO Terms of Interacting Partners?
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