SPOUT1 and MIR29B1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		SPOUT1	MIR29B1
Description		SPOUT domain containing methyltransferase 1	microRNA 29b-1
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Cytoplasm Spindle Pole Centrosome Mitotic Spindle	Extracellular Space Nucleus Cytoplasm Mitochondrion Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity MiRNA Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Cell Cycle Posttranscriptional Regulation Of Gene Expression Methylation Production Of MiRNAs Involved In Gene Silencing By MiRNA Cell Division Maintenance Of Centrosome Location	Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Type III Interferon Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of MAPK Cascade Regulation Of DNA Methylation Positive Regulation Of Fat Cell Differentiation Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Protein Secretion Negative Regulation Of Protein Kinase B Signaling Regulation Of Membrane Repolarization Regulation Of Blood Vessel Remodeling Negative Regulation Of Circulating Fibrinogen Levels Negative Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Virus Negative Regulation Of Interleukin-32 Production Negative Regulation Of Extracellular Matrix Assembly Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Mesenchymal Stem Cell Proliferation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Cell Death Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Aorta Morphogenesis Negative Regulation Of Collagen Fibril Organization Negative Regulation Of Matrix Metallopeptidase Secretion Positive Regulation Of Metalloendopeptidase Activity Regulation Of Epithelium Regeneration Negative Regulation Of Metallopeptidase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Osteoblast Differentiation Negative Regulation Of Intestinal Epithelial Cell Development Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS			Pancreatic cancer ( 25086665) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		52 interacting genes: CSNK2B INCA1 MIR1-1 MIR106A MIR106B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR34A MIR34B MIR429 MIR7-1 MIR9-1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT PLK1	72 interacting genes: APOBEC3B C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 FAM98A FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PURA RBFOX2 RBM14 RBM4 RBM47 RBMS2 RTCB SF3B1 SF3B3 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 TRIM71 UPF1 UTP20 YBX1 YBX3 ZFR ZNF346
Entrez ID		51490	407024
HPRD ID		12935
Ensembl ID		ENSG00000198917	ENSG00000283797
Uniprot IDs		Q5T280
PDB IDs		4RG1
Enriched GO Terms of Interacting Partners?
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