HSD17B7 and BRSK1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		HSD17B7	BRSK1
Description		hydroxysteroid 17-beta dehydrogenase 7	BR serine/threonine kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Centrosome Synaptic Vesicle Cell Junction Presynaptic Active Zone Distal Axon
	Molecular Function	3-keto Sterol Reductase Activity Estradiol 17-beta-dehydrogenase Activity 5alpha-androstane-3beta,17beta-diol Dehydrogenase Activity 17-beta-hydroxysteroid Dehydrogenase (NADP+) Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity ATP Binding Protein Kinase Binding Gamma-tubulin Binding Tau Protein Binding Tau-protein Kinase Activity Protein Serine Kinase Activity
	Biological Process	Cholesterol Biosynthetic Process Estrogen Biosynthetic Process Androgen Metabolic Process	G2/M Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Signaling Neurotransmitter Secretion Axonogenesis Associative Learning Response To UV Response To Ionizing Radiation Regulation Of Neuron Projection Development Peptidyl-serine Phosphorylation Establishment Of Cell Polarity Neuron Differentiation Intracellular Signal Transduction Cellular Response To Glucose Starvation Regulation Of Synaptic Plasticity Regulation Of Axonogenesis Centrosome Duplication Microtubule Cytoskeleton Organization Involved In Establishment Of Planar Polarity Synaptic Vesicle Cycle Regulation Of Synaptic Vesicle Clustering
Pathways		Cholesterol biosynthesis
Drugs		NADH
Diseases
GWAS		Dupuytren's disease ( 28886342)	Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 19448619 26414677)
Interacting Genes		7 interacting genes: BRSK1 CA1 DTYMK GORAB GPAT4 PBRM1 VKORC1	9 interacting genes: BRCA1 CDC25B CDC25C DNAAF3 HSD17B7 HSPA1A MAPT PAK1 WEE1
Entrez ID		51478	84446
HPRD ID		05996	12533
Ensembl ID		ENSG00000132196	ENSG00000160469
Uniprot IDs		A0A024R913 P56937 Q9H9C0	Q8TDC3
PDB IDs
Enriched GO Terms of Interacting Partners?
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