UCHL5 and ADRM1

Number of citations of the paper that reports this interaction (PubMedID 16501559)
201

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid, in vivo)

		UCHL5	ADRM1
Description		ubiquitin C-terminal hydrolase L5	ADRM1 26S proteasome ubiquitin receptor
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Ino80 Complex Cytosolic Proteasome Complex	Proteasome Complex Nucleoplasm Cytosol Plasma Membrane Proteasome Regulatory Particle, Lid Subcomplex
	Molecular Function	RNA Binding Thiol-dependent Deubiquitinase Endopeptidase Inhibitor Activity Protein Binding Proteasome Binding	Protease Binding Protein Binding Ubiquitin Binding Endopeptidase Activator Activity Proteasome Binding
	Biological Process	DNA Repair DNA Recombination Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Endopeptidase Activity Protein Deubiquitination Lateral Ventricle Development Midbrain Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Smoothened Signaling Pathway Forebrain Morphogenesis Regulation Of Proteasomal Protein Catabolic Process	Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Endopeptidase Activity Proteasome Assembly
Pathways		Downregulation of TGF-beta receptor signaling UCH proteinases UCH proteinases	UCH proteinases Ub-specific processing proteases
Drugs
Diseases
GWAS		Cannabis dependence ( 21668797)	Prostate cancer ( 23535732)
Interacting Genes		102 interacting genes: ACTN4 ADRM1 ANP32B ANP32E ANXA1 ANXA4 ANXA7 ANXA8 ANXA8L1 APP ARG1 ASPRV1 CALM1 CAP1 CAPZA1 CASP14 CDSN CFL1 CSTA DSC1 DSC3 DSP DUSP14 E2F1 E2F2 E2F3 EEF1G EEF2 EIF4A1 EPPK1 FLG GSTM3 H4-16 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HAUS7 HBA1 HBA2 HBB HSPB1 IDE IGHG1 IVL KDM1A KRT12 KRT19 KRT26 KRT28 KRT73 KRT78 KRT80 LMNA MAP3K1 NACA OGT PJA1 PKM PKP1 PLA2G2A PNP POF1B PRDX6 PSMD8 RAB7A RBCK1 RFFL S100A14 S100A16 S100A7 SERPINB12 SERPINB3 SERPINB5 SET SMAD2 SMAD3 SMAD7 TCF7 TGM3 TPI1 TRIM27 TRIM46 TRIM54 TRIM55 TRIM63 TUBA4A TXN TXN2 UBC USP28 YWHAZ ZBED1	24 interacting genes: APP ATP6V0D2 CDC42 DDI1 EGFR MAILR MX1 PRKN PSMD1 PSMD14 PSMD2 PSMD4 RAD23A RAD23B RPN1 RPN2 SGTA SMURF1 STUB1 UBC UBE3A UBQLN1 UBQLN2 UCHL5
Entrez ID		51377	11047
HPRD ID		10293	06440
Ensembl ID		ENSG00000116750	ENSG00000130706
Uniprot IDs		Q9Y5K5	A0A087WX59 Q16186
PDB IDs		3A7S 3IHR 3RII 3RIS 3TB3 4UEL 4UEM 4UF5 4UF6 4WLP	2KQZ 2KR0 2L5V 2MKZ 2NBV 4UEL 4UEM 4WLQ 4WLR 5IRS 5V1Y 5V1Z 5YMY 6CO4 6OI4 6UYI 6UYJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?