TNFRSF12A and TRAF5

Number of citations of the paper that reports this interaction (PubMedID 12529173)
68

Data Source:
HPRD (two hybrid, in vitro)

		TNFRSF12A	TRAF5
Description		TNF receptor superfamily member 12A	TNF receptor associated factor 5
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Signaling Receptor Complex
	Molecular Function	Protein Binding	Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding
	Biological Process	Angiogenesis Apoptotic Process Cell Adhesion Cell Differentiation Positive Regulation Of Apoptotic Process Regulation Of Wound Healing Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Apoptotic Process Signal Transduction Positive Regulation Of Cell Population Proliferation Signal Transduction Involved In Regulation Of Gene Expression Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade MRNA Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination Interleukin-17-mediated Signaling Pathway
Pathways		TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs
Diseases
GWAS			Household income (MTAG) ( 31844048)
Interacting Genes		8 interacting genes: KRTAP3-3 RAC1 SLC30A2 TNFSF12 TRAF1 TRAF2 TRAF3 TRAF5	66 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 CDC37 CIB3 COG7 COMMD3 DGKH ENOX2 FAM9A FBXO28 GAS8 GOLGA2 GORASP2 HOMER1 HSD17B10 HSF2BP LMO4 LNX1 LTBR MAP3K14 MAP3K5 MDM2 MEOX2 NMI NTAQ1 NUMBL ODF2 PIAS2 PIBF1 PICK1 PSMA1 RAD23A RIPK1 RIPK2 RNF111 RNF4 SDCBP SEC13 SERPINB9 SUMO1 TBK1 TDP2 THAP1 THAP7 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 YPEL5 ZFAND6 ZNF655
Entrez ID		51330	7188
HPRD ID		05801	03834
Ensembl ID		ENSG00000006327	ENSG00000082512
Uniprot IDs		Q9NP84	O00463
PDB IDs		2EQP 2KMZ 2RPJ	7L3L
Enriched GO Terms of Interacting Partners?
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