TIMMDC1 and CYP4F12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TIMMDC1	CYP4F12
Description		translocase of inner mitochondrial membrane domain containing 1	cytochrome P450 family 4 subfamily F member 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Monooxygenase Activity Iron Ion Binding Protein Binding Arachidonic Acid Monooxygenase Activity Arachidonic Acid Epoxygenase Activity Alkane 1-monooxygenase Activity Heme Binding Leukotriene-B4 20-monooxygenase Activity Aromatase Activity
	Biological Process		Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Renal Water Homeostasis Pressure Natriuresis Fatty Acid Metabolic Process Xenobiotic Metabolic Process Arachidonic Acid Metabolic Process Epoxygenase P450 Pathway Leukotriene B4 Catabolic Process Vitamin E Metabolic Process Menaquinone Catabolic Process Phylloquinone Catabolic Process Vitamin K Catabolic Process Sodium Ion Homeostasis
Pathways		Complex I biogenesis	Fatty acids Eicosanoids
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244 24076602) Primary biliary cholangitis ( 30643196) Primary biliary cirrhosis ( 22961000) Systemic lupus erythematosus ( 33272962 28714469) Systemic sclerosis ( 31672989)	Glioma ( 34319593) LDL cholesterol levels ( 32203549)
Interacting Genes		70 interacting genes: AGR3 ANKRD46 APOC2 APOC4 APOL3 APP ARL6IP6 ATP6AP2 BCAP31 C14orf180 C3orf52 C4orf3 C5orf46 CCL4 CDS2 CMTM2 CREB3L1 CYP4F12 DCBLD2 DIABLO DRAM1 EPGN FAM20B FAM210B FATE1 FXYD3 GJB2 GPR151 GPR152 GPX8 HGS HSD17B13 IFNA2 KIR2DL4 LHFPL5 MARCHF5 MFSD14B MFSD5 NDUFB11 NINJ1 PEX5 PIGF PTPN1 PTPRN RNF24 SCAMP5 SCD SERF1A SERF1B SERP2 SLC35E4 SLC35F6 SMO ST6GAL2 STX12 STX6 TMEM144 TMEM14B TMEM176A TMEM199 TMEM203 TMEM239 TMEM31 TMEM54 TMEM65 TMEM86A TVP23B UNC93A YIF1A YIPF1	5 interacting genes: HSPA6 MEOX2 SLC44A2 SOD2 TIMMDC1
Entrez ID		51300	66002
HPRD ID		12817	07102
Ensembl ID		ENSG00000113845	ENSG00000186204
Uniprot IDs		C9JU35 Q9NPL8	Q9HCS2
PDB IDs
Enriched GO Terms of Interacting Partners?
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