PCYT1A and VKORC1L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PCYT1A	VKORC1L1
Description		phosphate cytidylyltransferase 1A, choline	vitamin K epoxide reductase complex subunit 1 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Glycogen Granule	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Choline-phosphate Cytidylyltransferase Activity Protein Binding Calmodulin Binding Phosphatidylcholine Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Quinone Binding
	Biological Process	Phosphatidylcholine Biosynthetic Process CDP-choline Pathway	Peptidyl-glutamic Acid Carboxylation Cellular Response To Oxidative Stress Vitamin K Metabolic Process
Pathways		Synthesis of PC	Metabolism of vitamin K
Drugs		Choline Choline salicylate	Menadione
Diseases
GWAS		Mean platelet volume ( 32888494)	Calcium levels ( 24068962) Corneal structure ( 23291589) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 30591961) Neutrophil count ( 32888494)
Interacting Genes		16 interacting genes: ACTB AGTRAP CASP6 CASP8 FKBP7 GYS1 MAGEA3 MOB1A MOB3C PCYT1B RNF8 SCAMP1 SDCBP SNAPIN TNFRSF10D VKORC1L1	11 interacting genes: AQP6 CISD2 ERGIC3 GORAB GPX8 MRM1 MS4A3 MTIF3 PCYT1A PCYT1B TMEM80
Entrez ID		5130	154807
HPRD ID		00438	12312
Ensembl ID		ENSG00000161217	ENSG00000196715
Uniprot IDs		B4E322 P49585	A8K0F7 Q8N0U8
PDB IDs
Enriched GO Terms of Interacting Partners?
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