GOLM1 and HGFAC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GOLM1	HGFAC
Description		golgi membrane protein 1	HGF activator
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space Rough Endoplasmic Reticulum Cytosol
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Protein Binding Serine-type Peptidase Activity
	Biological Process	Nucleus Organization Regulation Of Lipid Metabolic Process	Proteolysis Blood Coagulation Zymogen Activation
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	MET Receptor Activation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Logical memory (delayed recall) in normal cognition ( 29274321)	Alanine aminotransferase levels ( 33547301) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 30072576) Coronary artery disease ( 29212778) Crohn's disease ( 26192919) Estimated glomerular filtration rate ( 31152163 31015462) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422 26561523) Gamma glutamyl transferase levels ( 29403010 33339817) Height ( 31562340 29782485) Hepatocyte growth factor levels ( 27989323 25998175) Inflammatory bowel disease ( 26192919) Iron status biomarkers (total iron binding capacity) ( 33536631) LDL cholesterol levels ( 32203549) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Pulse pressure ( 27841878 30578418) Serum total protein level ( 29403010) Triglyceride levels ( 32203549 32154731 29403010 33339817 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531)
Interacting Genes		79 interacting genes: ABI3 AIG1 ANKRD46 ARTN ASPH B3GNT4 BCL2L1 C1orf174 C1QL4 CDIPT CIAO1 CLDN4 CLDND2 CLK1 CNPY3 DCK DCTN2 DESI1 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 FUT9 GALNT15 GAST GEMIN7 GET3 GLB1 GRIK5 GUCA2A HGFAC HMGB1 HSD17B13 IGFBP5 INSIG2 JAGN1 KCNE3 LAT LSM12 MED22 MIP NDUFV2 NEU1 NINJ1 NIPSNAP3A NRSN2 PGRMC1 RACK1 RIPPLY2 RPA2 RPL13A SFTPC SLC13A5 SLC30A3 SLC35B2 SLC40A1 SLC5A4 SLCO3A1 ST6GAL2 STRIT1 SYT1 TF THSD7A TLE1 TMEM109 TMEM140 TMEM147 TMEM176A TMEM86B TMEM98 TMPO TMUB1 TMUB2 TSG101 VSTM1 ZFAND3	10 interacting genes: APPBP2 CCHCR1 F2 GOLM1 HGF KLKB1 SLC30A2 SPINT1 SPINT2 VSIG1
Entrez ID		51280	3083
HPRD ID		08428	05184
Ensembl ID		ENSG00000135052	ENSG00000109758
Uniprot IDs		B3KNK9 Q8NBJ4	D6RAR4 Q04756
PDB IDs			1YBW 1YC0 2R0K 2R0L 2WUB 2WUC 3K2U
Enriched GO Terms of Interacting Partners?
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