PAIP2 and ELAVL1

Number of citations of the paper that reports this interaction (PubMedID 15175342)
25

Data Source:
HPRD (in vivo, in vitro)

		PAIP2	ELAVL1
Description		poly(A) binding protein interacting protein 2	ELAV like RNA binding protein 1
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GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Cytoplasmic Stress Granule Membrane Cytoplasmic Vesicle Postsynapse Glutamatergic Synapse Ribonucleoprotein Complex
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding MRNA Binding Protein Binding Translation Repressor Activity	RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Protein Kinase Binding MiRNA Binding MRNA 3'-UTR AU-rich Region Binding Protein Homodimerization Activity
	Biological Process	Spermatogenesis Memory Negative Regulation Of Translation Negative Regulation Of Translational Initiation Regulation Of Long-term Synaptic Potentiation	Protein Import Into Nucleus Posttranscriptional Gene Silencing Positive Regulation Of Translation MRNA Stabilization Protein Homooligomerization Negative Regulation Of Gene Silencing By MiRNA 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Population Maintenance
Pathways			HuR (ELAVL1) binds and stabilizes mRNA mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 26426971) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Malaria ( 31844061)	Blood protein levels ( 28240269)
Interacting Genes		7 interacting genes: APP ELAVL1 PABPC1 PABPC5 RPL11 TRIM54 UBR5	39 interacting genes: ANP32A ANP32B APOE C12orf75 CARM1 CELF2 CHEK2 CTNNB1 DNM2 ERG FAF2 GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP2 PTGS2 RBFOX2 SDCBP SET SHANK3 SREK1 TNPO1 TNPO2 TRIM21 VCP VEGFA
Entrez ID		51247	1994
HPRD ID		05726	16025
Ensembl ID		ENSG00000120727	ENSG00000066044
Uniprot IDs		Q49AE6 Q9BPZ3	Q15717
PDB IDs		1JGN 3KUS 3KUT	3HI9 4ED5 4EGL 4FXV 5SZW 6G2K 6GC5 6GD1 6GD2 6GD3
Enriched GO Terms of Interacting Partners?
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