CLDN18 and STAG1

		CLDN18	STAG1
Description		claudin 18	stromal antigen 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Nuclear Body Mitotic Spindle Pole
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Chromatin Binding Protein Binding
	Biological Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Response To Ethanol Negative Regulation Of Bone Resorption Digestive Tract Development Bicellular Tight Junction Assembly TNFSF11-mediated Signaling Pathway Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Osteoclast Development	Sister Chromatid Cohesion Cell Division Mitotic Spindle Assembly
Pathways		Tight junction interactions	Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Metabolite levels ( 23823483)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein B levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 28892062 25673413) Body shape index ( 34021172) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Central corneal thickness ( 32528159 31798171 29760442) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 29212778 30104761) Dentures ( 31235808) General risk tolerance (MTAG) ( 30643258) HDL cholesterol ( 30275531) Height ( 25282103) Intraocular pressure ( 29617998) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Multisite chronic pain ( 33830993 31194737) Myocardial infarction ( 33532862) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Plateletcrit ( 32888494) Schizophrenia ( 28991256 25056061 29483656 30285260) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		3 interacting genes: EHHADH PMP22 STAG1	13 interacting genes: ASPH CALM1 CEP63 CLDN18 GUK1 MSL2 RAD21 SMAD2 SMAD9 SMC1B STAG2 VDR WFDC5
Entrez ID		51208	10274
HPRD ID		13066	05076
Ensembl ID		ENSG00000066405	ENSG00000118007
Uniprot IDs		P56856	Q4LE48 Q8WVM7
PDB IDs			5QSM 5QSN 5QSO 5QSP 5QSQ 5QSR 5QSS 5QST 5QSU 5QSV 5QSW 5QSX 5QSY 5QSZ 6QB5 6R7O 6RRC 6RRK 6WG3
Enriched GO Terms of Interacting Partners?
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