PCNT and PFKL

		PCNT	PFKL
Description		pericentrin	phosphofructokinase, liver type
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Microtubule Membrane Centriolar Satellite	Extracellular Region Cytosol 6-phosphofructokinase Complex Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Calmodulin Binding Molecular Adaptor Activity	6-phosphofructokinase Activity Protein Binding ATP Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Signal Transduction Cilium Assembly Positive Regulation Of Intracellular Protein Transport	Fructose 6-phosphate Metabolic Process Glycolytic Process Response To Glucose Fructose 1,6-bisphosphate Metabolic Process Negative Regulation Of Insulin Secretion Canonical Glycolysis
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Neutrophil degranulation Glycolysis
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) S100 calcium-binding protein levels ( 33227023) Treatment resistant depression ( 30468137)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Rheumatoid arthritis ( 21505073)
Interacting Genes		21 interacting genes: AKAP9 CALM1 CALM2 CCP110 CDK12 CEP55 COL6A1 DISC1 HPRT1 NDUFV3 PCM1 PDE9A PFKL PKNOX1 RAC3 S100B SH3BGR TP53BP1 TUBG1 TUBGCP2 TUBGCP3	16 interacting genes: APP ATN1 COPS6 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PCNT PFKM PRPF40A SHANK3 SUMO2 TESK1 TNFAIP3 YWHAQ
Entrez ID		5116	5211
HPRD ID		05804	01385
Ensembl ID		ENSG00000160299	ENSG00000141959
Uniprot IDs		O95613	P17858 Q7L2M7
PDB IDs
Enriched GO Terms of Interacting Partners?
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