DYNC1LI1 and NUP85

Number of citations of the paper that reports this interaction (PubMedID 10893222)
59

Data Source:
HPRD (in vivo)

		DYNC1LI1	NUP85
Description		dynein cytoplasmic 1 light intermediate chain 1	nucleoporin 85
Image
GO Annotations	Cellular Component	Kinetochore Spindle Pole Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane	Kinetochore Nuclear Envelope Nucleoplasm Spindle Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane
	Molecular Function	RNA Binding Protein Binding ATP Binding GTP Binding GDP Binding Dynein Heavy Chain Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Microtubule Cytoskeleton Organization Microtubule-based Movement Cell Cycle Cell Division Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint	MRNA Export From Nucleus Protein Import Into Nucleus Lamellipodium Assembly Positive Regulation Of Transcription, DNA-templated Macrophage Chemotaxis Nephron Development
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RHO GTPases Activate Formins Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Low density lipoprotein cholesterol levels ( 33339817)	Systemic sclerosis ( 31672989)
Interacting Genes		14 interacting genes: BRCA2 CMTM6 CMTM7 FBXL2 GPD1L IKBKG NOP56 NUP85 OGT PGAM2 RAB4A REL SUSD5 TRIM71	6 interacting genes: DYNC1LI1 EEF1G GET4 PIK3R1 PRKACA VIM
Entrez ID		51143	79902
HPRD ID		10917	01363
Ensembl ID		ENSG00000144635	ENSG00000125450
Uniprot IDs		E9PHI6 Q9Y6G9	J3KT10 Q9BW27
PDB IDs		6B9H 6PSD 6PSE	5A9Q
Enriched GO Terms of Interacting Partners?
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