RLIM and PDLIM1

Number of citations of the paper that reports this interaction (PubMedID 11882901)
64

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		RLIM	PDLIM1
Description		ring finger protein, LIM domain interacting	PDZ and LIM domain 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Transcription Repressor Complex	Stress Fiber Transcription Regulator Complex Cytoplasm Cytoskeleton Adherens Junction Focal Adhesion Z Disc Filamentous Actin
	Molecular Function	Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Random Inactivation Of X Chromosome Regulation Of Dosage Compensation By Inactivation Of X Chromosome	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Fibroblast Migration Maintenance Of Cell Polarity Actin Cytoskeleton Organization Establishment Or Maintenance Of Actin Cytoskeleton Polarity Stress Fiber Assembly Positive Regulation Of Transcription, DNA-templated Muscle Structure Development Cell-cell Adhesion
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Brain asymmetrical skew (horizontal) ( 33836062)	Hemoglobin ( 32888494) Mean platelet volume ( 32888494 27863252) Suicide risk ( 21041247) White blood cell count ( 32888494)
Interacting Genes		29 interacting genes: BRF1 ESR1 ISL1 LDB1 LDB2 LHX1 LHX2 LHX3 LIMK1 LMO2 LNX2 MDM2 PDLIM1 REXO1 RPS14 SIN3A SMAD7 SMURF2 SNX17 SS18L1 STAT6 TERF1 TNFAIP3 UBC UBE2D1 UBE2D3 UBE2D4 UBE2E1 UBE2K	14 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 PTGER4 RLIM RPS6KA5 STK35 SUPT4H1 VIM
Entrez ID		51132	9124
HPRD ID		02304	09326
Ensembl ID		ENSG00000131263	ENSG00000107438
Uniprot IDs		Q9NVW2	O00151 V9HW92
PDB IDs		6W7Z 6W9A 6W9D	1X62 2PKT
Enriched GO Terms of Interacting Partners?
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