NDUFAF1 and TMEM86B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NDUFAF1	TMEM86B
Description		NADH:ubiquinone oxidoreductase complex assembly factor 1	transmembrane protein 86B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Cytosol	Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Unfolded Protein Binding	Protein Binding Ether Hydrolase Activity Identical Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone NADH Dehydrogenase Complex Assembly Mitochondrial Respiratory Chain Complex I Assembly Chaperone-mediated Protein Complex Assembly Protein-containing Complex Assembly	Phosphatidylcholine Acyl-chain Remodeling Ether Lipid Metabolic Process
Pathways		Complex I biogenesis	Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Eosinophil percentage of white cells ( 27863252) Ulcerative colitis ( 28067908 23128233)	Mean reticulocyte volume ( 32888494) Phosphatidylethanolamine-ether levels ( 31551469) Serum metabolite levels ( 33031748) Systemic lupus erythematosus ( 33536424 28714469)
Interacting Genes		10 interacting genes: JMJD7-PLA2G4B MAGEA11 NVL PNLIPRP1 SLC30A2 SLC30A4 STX8 TMEM86B TMEM97 YIPF6	105 interacting genes: AQP6 ARL13B ARL6IP6 ASGR2 BCL2L13 BIK BMP10 C2CD2L CCDC167 CCDC34 CCL4 CD53 CD79A CLRN1 CYB5B DHRSX DNAJC30 EBP ERGIC3 ERP29 EVI2B F11R FAM209A FAXDC2 FKBP7 FXYD6 GJA1 GJA4 GJA8 GOLM1 GPR37L1 GPX8 GUCA2A HIBADH HSD17B13 IER3IP1 IFITM3 KIR2DL3 LAPTM4B LIME1 LSS LY6D MARCHF2 MFF MGST3 MMGT1 MS4A14 MSMO1 MUC1 NDUFAF1 NEMP1 NINJ2 ORMDL2 OTULINL PEX11G PGRMC2 PIGF PLN PSCA PTPN1 PTPN9 RHBDD1 RHOT2 RPRM RTP2 SEC22B SERINC2 SFRP1 SFT2D1 SFXN5 SLC10A6 SLC29A2 SLC35G2 SLC39A9 SMIM1 SNORC SSMEM1 STOM STX12 STX6 STX8 TEX29 THAP4 THBD TIMM23 TMEM106A TMEM107 TMEM120A TMEM14A TMEM14C TMEM203 TMEM237 TMEM248 TMEM52B TMEM60 TMPRSS2 TMX2 TREX1 TSNARE1 USE1 VAMP2 VAMP3 VAMP5 VAPA ZDHHC22
Entrez ID		51103	255043
HPRD ID		09500	14540
Ensembl ID		ENSG00000137806	ENSG00000180089
Uniprot IDs		A0A024R9L0 Q9Y375	Q8N661
PDB IDs
Enriched GO Terms of Interacting Partners?
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