PCMT1 and CYSLTR2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		PCMT1	CYSLTR2
Description		protein-L-isoaspartate (D-aspartate) O-methyltransferase	cysteinyl leukotriene receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome Extracellular Vesicle	Cellular_component Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity Protein Binding Cadherin Binding	Cysteinyl Leukotriene Receptor Activity Leukotriene Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding G Protein-coupled Peptide Receptor Activity
	Biological Process	Protein Methylation Protein Repair	Immune Response Neuropeptide Signaling Pathway Regulation Of Catalytic Activity Leukotriene Signaling Pathway Cellular Response To Glucagon Stimulus
Pathways		Protein repair	Glucagon signaling in metabolic regulation Leukotriene receptors G alpha (q) signalling events G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production LTC4-CYSLTR mediated IL4 production
Drugs		S-adenosyl-L-homocysteine	Nedocromil Leukotriene C4 Leukotriene D4
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Serum metabolite levels ( 33031748) Subcortical volume (MOSTest) ( 32665545)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Systemic juvenile idiopathic arthritis ( 27927641)
Interacting Genes		13 interacting genes: AGTR1 APOA1 APOE CCR2 CHD3 CLP1 CREBBP CYSLTR2 DLG4 IQCB1 RPIA TAAR1 VKORC1	19 interacting genes: ATP5MC2 DBI ENO1 GNAS GRIK1 HSP90B1 KRTAP1-1 LNX1 MTUS2 NCKIPSD PCDH9 PCMT1 RNASEK RNF144A RTN4 SVOP TTC19 YIPF6 YWHAE
Entrez ID		5110	57105
HPRD ID		08908	09293
Ensembl ID		ENSG00000120265	ENSG00000152207
Uniprot IDs		A0A0A0MRJ6 A0A3F2YNX8 B7Z972 F6S8N6 P22061	A4ZKH2 Q5KU17 Q9NS75
PDB IDs		1I1N 1KR5
Enriched GO Terms of Interacting Partners?
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