UBXN1 and HOMER2

Number of citations of the paper that reports this interaction (PubMedID 15944415)
10

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		UBXN1	HOMER2
Description		UBX domain protein 1	homer scaffold protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Dendrite VCP-NPL4-UFD1 AAA ATPase Complex Neuronal Cell Body	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Dendrite Stereocilium Tip Neuronal Cell Body Intracellular Organelle Apical Part Of Cell Glutamatergic Synapse
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Protein Ligase Binding K48-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding ATPase Binding K6-linked Polyubiquitin Modification-dependent Protein Binding Proteasome Regulatory Particle Binding	Actin Binding Protein Binding Protein Domain Specific Binding Synaptic Receptor Adaptor Activity G Protein-coupled Glutamate Receptor Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein K48-linked Deubiquitination Negative Regulation Of ERAD Pathway Negative Regulation Of Ubiquitin-specific Protease Activity	G Protein-coupled Glutamate Receptor Signaling Pathway Sensory Perception Of Sound Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Calcium-mediated Signaling Using Intracellular Calcium Source Behavioral Response To Cocaine Chemical Homeostasis Within A Tissue Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Tourette syndrome ( 30818990)
Interacting Genes		20 interacting genes: ACOT7 ACVR1 BARD1 BMPR1B BRCA1 FAM189A2 HMGB1 HOMER2 PLA2G4A PLAA POLR3C RAD23A SMAD1 SMURF1 TGFBR1 TRIM39 UBC UBE2I UBQLN1 UBQLN2	15 interacting genes: ABI3 AGAP2 APP DBN1 FXR1 GRM1 ITPR1 KPNA2 LZTS2 PALLD PJA1 RYR1 SMURF1 UBXN1 VKORC1
Entrez ID		51035	9455
HPRD ID		11266	07269
Ensembl ID		ENSG00000162191	ENSG00000103942
Uniprot IDs		A0A024R539 A0A024R598 A0A087WTZ5 Q04323	Q9NSB8
PDB IDs
Enriched GO Terms of Interacting Partners?
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