SLC35C2 and SACM1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC35C2	SACM1L
Description		solute carrier family 35 member C2	SAC1 like phosphatidylinositide phosphatase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum-plasma Membrane Contact Site
	Molecular Function	Antiporter Activity	Phosphatidylinositol-3-phosphatase Activity Protein Binding Phosphatase Activity Phosphatidylinositol Bisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Phosphatidylinositol-4-phosphate Phosphatase Activity
	Biological Process	Negative Regulation Of Gene Expression UDP-glucose Transmembrane Transport Protein O-linked Fucosylation Positive Regulation Of Notch Signaling Pathway	Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Dephosphorylation
Pathways			Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Macular telangiectasia type 2 ( 33654266) Response to anti-depressant treatment in major depressive disorder ( 22041458) Serum metabolite levels ( 33031748) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		92 interacting genes: ACSL5 ADIPOQ AGPAT3 AGPAT4 APOD ARL6IP1 ASGR1 ATP13A1 BCL2L2 BMP10 C14orf180 C2 C4orf3 CCDC167 CLDN19 CMTM5 CNIH1 COL4A5 CREB3 CREB3L1 CYB561 CYBC1 DNAJC30 EFNA5 EMP3 FAM3C FDFT1 FFAR2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP5 GOLT1A GPR152 ITGAM LAT LEPROTL1 LHFPL5 LPAR3 MAL MAL2 MALL MS4A1 NRM ORMDL1 ORMDL3 PDCD1LG2 PEX16 PLN PLP2 PNLIPRP1 PRB1 RUSF1 SACM1L SEC22A SEC22B SELENOK SERP1 SLC10A6 SLC12A5 SLC12A7 SLC30A3 SLC35F1 SLC66A1 SMCO4 SSMEM1 STRIT1 STX3 SYNDIG1 SYS1 TAP1 THBD TMEM107 TMEM14B TMEM239 TMEM31 TMEM50B TMEM65 TMEM86A TPRG1 TSNARE1 TSPAN2 TSPAN33 TVP23B UNC93B1 UPK1B VAPB VEGFA VTI1B YIF1A YIPF4 YIPF6	35 interacting genes: ACKR2 AQP6 ARL13B CD79A COPA COPB2 COPG1 CREB3 CREB3L1 DHRS7 EBP FFAR2 FMO3 GPR151 GPR152 HSD17B13 JAGN1 LMNA MFF MFSD14B MTERF2 ODF4 PRKCA RNF19B RTN3 SCN3B SLC10A1 SLC10A6 SLC35A5 SLC35C2 SLC7A1 TMEM167B TMX2 VEZT ZFYVE27
Entrez ID		51006	22908
HPRD ID		15371	07587
Ensembl ID		ENSG00000080189	ENSG00000211456
Uniprot IDs		B7Z6R4 Q9NQQ7	B4DVV3 E9PGZ4 Q9NTJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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