MED31 and NAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MED31	NAF1
Description		mediator complex subunit 31	nuclear assembly factor 1 ribonucleoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex Core Mediator Complex	Nucleoplasm Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm
	Molecular Function	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity	RNA Binding Protein Binding Identical Protein Binding Telomerase RNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Negative Regulation Of Fibroblast Proliferation Limb Development	SnoRNA Guided RRNA Pseudouridine Synthesis Box H/ACA SnoRNP Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Ribosome Biogenesis RNA Stabilization Positive Regulation Of Telomerase Activity Telomerase RNA Stabilization Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Telomerase RNA Localization To Cajal Body Telomerase Holoenzyme Complex Assembly
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Chronotype ( 30696823) Colorectal cancer ( 25023989) Daytime nap ( 33568662) Hair morphology ( 19896111) Leukocyte telomere length ( 32109421 31171785) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) TPE interval (recovery after exercise) ( 32386560)
Interacting Genes		59 interacting genes: AGR2 ANXA7 ASCC2 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NAF1 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 TLE5 UBE2B WDCP ZBTB45 ZSCAN1	26 interacting genes: BOLL CSNK2A1 DAB1 ELOA FAM168A HERPUD2 KRTAP19-3 KRTAP19-7 KRTAP6-1 KRTAP6-2 MAGED1 MED31 MSX2 RAMAC RBFOX2 SCARNA13 SCARNA8 SH3RF1 SNORA74A SNX33 SORBS3 SS18L1 TENT5B TLE5 UBE2I YWHAE
Entrez ID		51003	92345
HPRD ID		14382	10054
Ensembl ID		ENSG00000108590	ENSG00000145414
Uniprot IDs		Q9Y3C7	Q96HR8
PDB IDs			2EQN
Enriched GO Terms of Interacting Partners?
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