PCBP1 and IGF2BP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PCBP1	IGF2BP3
Description		poly(rC) binding protein 1	insulin like growth factor 2 mRNA binding protein 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Translation Regulator Activity MRNA 5'-UTR Binding
	Biological Process	Regulation Of Gene Expression Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process	Regulation Of Cytokine Production Translation Nervous System Development Anatomical Structure Morphogenesis Regulation Of Gene Expression Negative Regulation Of Translation MRNA Transport Regulation Of RNA Metabolic Process
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)	Birth weight ( 31043758 27680694) Height ( 28552196 20881960 25282103 23563607) Hip circumference adjusted for BMI ( 34021172 25673412) Infant length ( 25281659) Offspring birth weight ( 31043758) Personality dimensions ( 23903073) Tau burden ( 33426524) Type 2 diabetes ( 30297969) White blood cell count ( 32888494)
Interacting Genes		51 interacting genes: ANP32A APP CAV3 CELF2 CELF3 DARS1-AS1 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL HYPK IGF2BP3 KLF1 LMNA MATR3 MOGS NOVA1 OGT PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM3 RBM42 RBPMS2 SNCG SNRPA SRPK2 SRSF3 TCERG1 TLE5 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	78 interacting genes: DUX4 MEOX2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MKRN2 OGT PCBP1 PIH1D2
Entrez ID		5093	10643
HPRD ID		03128	16306
Ensembl ID		ENSG00000169564	ENSG00000136231
Uniprot IDs		Q15365 Q53SS8	O00425
PDB IDs		1WVN 1ZTG 3VKE	2E44 6FQ1 6FQR 6GQE 6GX6
Enriched GO Terms of Interacting Partners?
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