PBX2 and RIPPLY2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PBX2	RIPPLY2
Description		PBX homeobox 2	ripply transcriptional repressor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Transcription Factor Binding	Protein Binding
	Biological Process	Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Animal Organ Morphogenesis Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Neuron Development	Negative Regulation Of Transcription By RNA Polymerase II Ossification Somitogenesis Notch Signaling Pathway Determination Of Left/right Symmetry Embryonic Pattern Specification Somite Rostral/caudal Axis Specification Post-anal Tail Morphogenesis Bone Morphogenesis
Pathways
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Anxiety ( 33859377) Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Coronary artery disease ( 33020668) Crohn's disease ( 23266558) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Moderate to vigorous physical activity levels ( 29899525) Prostate cancer ( 23535732) Refractive error ( 32231278) Rheumatic heart disease ( 32488134) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172)
Interacting Genes		39 interacting genes: BAIAP2 BFSP2 BLOC1S1 BLOC1S5 BRMS1L CARD9 CCDC88B CDCA7L CENPBD1P COPS6 DCTN3 EFHC1 ELP1 FAM90A1 HOXA1 HOXA5 HOXA9 HOXB5 HOXB8 HOXC5 HOXC8 HOXC9 MCRS1 MSC MTREX NEU1 NOTCH4 NUP62 PBX1 PKNOX1 PPFIBP1 RIPPLY2 RPL4 RPS6KC1 SMYD3 UBE2E1 ZCWPW2 ZDHHC7 ZNF587	11 interacting genes: AVPI1 C3orf36 GOLM1 KASH5 NDUFB7 PBX2 PBX4 PGM3 SNAP91 SYNE4 TFG
Entrez ID		5089	134701
HPRD ID		08890	16658
Ensembl ID		ENSG00000204304	ENSG00000203877
Uniprot IDs		A0A024RCR3 P40425	Q5TAB7
PDB IDs
Enriched GO Terms of Interacting Partners?
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