PAWR and SLC5A7

Number of citations of the paper that reports this interaction (PubMedID 15090548)
5

Data Source:
HPRD (in vivo, in vitro)

		PAWR	SLC5A7
Description		pro-apoptotic WT1 regulator	solute carrier family 5 member 7
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Actin Filament Plasma Membrane Actin Cytoskeleton	Plasma Membrane Integral Component Of Membrane Axon Dendrite Neuromuscular Junction Perikaryon Synapse
	Molecular Function	Transcription Corepressor Activity Actin Binding Protein Binding Enzyme Binding Leucine Zipper Domain Binding	Choline:sodium Symporter Activity Choline Transmembrane Transporter Activity Choline Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of B Cell Proliferation Negative Regulation Of T Cell Proliferation Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Fibroblast Proliferation Negative Regulation Of T Cell Receptor Signaling Pathway Actin Filament Bundle Assembly Apoptotic Signaling Pathway Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Cellular Senescence	In Utero Embryonic Development Sodium Ion Transport Neurotransmitter Transport Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Acetylcholine Biosynthetic Process Choline Transport Transmembrane Transport
Pathways			Acetylcholine Neurotransmitter Release Cycle Transport of bile salts and organic acids, metal ions and amine compounds Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: AATF ATP5F1C DAPK3 DRD2 HSPA5 PML PRKCZ RRAS2 SLC5A7 SPSB1 SPSB2 SPSB4 SQSTM1 TFPT THAP1 WT1	1 interacting genes: PAWR
Entrez ID		5074	60482
HPRD ID		09051	12294
Ensembl ID		ENSG00000177425	ENSG00000115665
Uniprot IDs		Q96IZ0	B2RCU2 B4DUU7 Q2T9H3 Q9GZV3
PDB IDs		2JK9
Enriched GO Terms of Interacting Partners?
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