ITSN2 and KXD1

Number of citations of the paper that reports this interaction (PubMedID 22558309)
25

Data Source:
BioGRID (two hybrid)

		ITSN2	KXD1
Description		intersectin 2	KxDL motif containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Plasma Membrane Clathrin-coated Pit Presynaptic Membrane Extracellular Exosome Intracellular Vesicle Presynapse	Lysosomal Membrane BORC Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Endocytosis Endosomal Transport Cell Differentiation Regulation Of Catalytic Activity Clathrin-dependent Synaptic Vesicle Endocytosis Positive Regulation Of Dendrite Extension	Vesicle-mediated Transport Lysosome Localization
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis RHOU GTPase cycle
Drugs
Diseases
GWAS		Asthma ( 29273806) Chromium levels ( 26025379) Diffuse large B cell lymphoma ( 25261932) Feeling fed-up ( 29500382) Low density lipoprotein cholesterol levels ( 32154731 33339817) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) SjÃ¶gren's syndrome ( 24097067) Total cholesterol levels ( 33339817)
Interacting Genes		77 interacting genes: AGT AHDC1 AMPH ANKRD17 B4GALT2 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DST EGFR EPS15L1 EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RAD9A RBMX REPS1 RNF20 ROCK1 RRM2 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	46 interacting genes: APPL1 ARHGDIG BORCS6 C4orf46 CCDC185 CCDC33 CEP170P1 CEP19 CEP63 COLGALT1 DYRK2 ELOA ELOA2 EWSR1 EXOC5 EXOC7 FXR2 GABARAPL1 HAUS1 IFT20 ING5 ITSN2 KRT81 LMO3 LNX1 LRRC45 MAB21L3 MAP1LC3A MAP1LC3B MCRS1 MOB1A MYH7 NIF3L1 NUDT18 RABGEF1 RNF183 RPL9 SRPK2 STX11 TCEA2 TPM1 TPM3 UTP6 ZBTB25 ZC4H2 ZNF417
Entrez ID		50618	79036
HPRD ID		09193	14526
Ensembl ID		ENSG00000198399	ENSG00000105700
Uniprot IDs		A6H8W8 Q9NZM3	A0A024R7M2 Q9BQD3
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO
Enriched GO Terms of Interacting Partners?
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