Description |
nitric oxide synthase 3 |
apolipoprotein E |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Arginine
- Citrulline
- Sapropterin
- Miconazole
- N,N-dimethylarginine
- L-N(omega)-Nitroarginine-2,4-L-diaminobutyric amide
- Canavanine
- 3-Bromo-7-Nitroindazole
- N-{(4S)-4-Amino-5-[(2-aminoethyl)amino]pentyl}-N'-nitroguanidine
- N-[3-(aminomethyl)benzyl]acetamidine
- 1,2,4-Triazole-Carboxamidine
- L-N(omega)-nitroarginine-(4R)-amino-L-proline amide
- S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea
- 7-Nitroindazole
- S-Ethylisothiourea
- 2-Aminothiazoline
- Se-Ethyl-Isoselenourea
- 2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine
- N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane
- Cacodylic acid
- 7-Nitroindazole-2-Carboxamidine
- 6-Nitroindazole
- N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine
- N(G)-Iminoethylornithine
- 5,6-Cyclic-Tetrahydropteridine
- S-Ethyl-N-Phenyl-Isothiourea
- S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea
- 6S-5,6,7,8-Tetrahydrobiopterin
- S-(Dimethylarsenic)Cysteine
- L-homoarginine
- S-Isopropyl-Isothiourea
- Nitroarginine
- 5-Nitroindazole
- N-(Chlorophenyl)-N'-hydroxyguanidine
- (3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine
- 5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE
- ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE
- N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE
- N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine
- Levamlodipine
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Diseases |
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GWAS |
- Coronary artery disease ( 29212778 30104761 26343387)
- Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
- Diastolic blood pressure ( 27841878 28739976 27618448)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Estimated glomerular filtration rate ( 31451708)
- Eyebrow thickness ( 26926045)
- Hypertension ( 27618448)
- Mean arterial pressure ( 27618448)
- Mean platelet volume ( 32888494)
- Medication use (agents acting on the renin-angiotensin system) ( 31015401)
- Medication use (beta blocking agents) ( 31015401)
- Medication use (calcium channel blockers) ( 31015401)
- Medication use (diuretics) ( 31015401)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Myocardial infarction ( 33532862)
- Offspring birth weight ( 31043758)
- Periventricular white matter hyperintensities ( 32517579)
- Platelet distribution width ( 32888494)
- Stroke ( 30383316)
- Systolic blood pressure ( 27841878 27618448 30578418)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
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Interacting Genes |
48 interacting genes:
A2M
ACTN2
ACTN4
AGTR1
AKT1
APOE
APP
BDKRB2
BDNF
CALM1
CAV1
CDC37
CEP55
EDNRB
EFEMP1
EFEMP2
ELAVL1
ELAVL3
EXOC6
EXOSC1
FIS1
GCDH
GOLGA2
H3-3A
HSP90AA1
HTRA1
IKZF3
IMMT
KANK2
MAGEA11
MAST1
MPRIP
NMT1
NOSIP
NOSTRIN
PAXIP1
PI4K2A
PPP2R5A
PSEN1
PSEN2
RHEB
RNF31
RNF32
SP1
ST13
TECR
TXNDC11
UMPS
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65 interacting genes:
A2M
ALB
ANKH
APOC2
APOC4
APP
ARFGAP1
CD1D
CD79A
CDC37
CEACAM1
CNTF
CSNK2A1
CST1
CTSB
CYP2C18
CYP2C8
ECSIT
ELAVL1
EPN2
FARSA
FBXL12
FOXG1
FXYD7
GCDH
HSP90AA1
HTRA1
IFIT3
IFIT5
IQSEC1
LCAT
LDLR
LINC02582
LONP1
LOXL4
LRP1
LRP2
LRP8
MAP2
MAPT
MAST1
MID1IP1
NEFM
NOS3
PCMT1
PDCD4
PLEKHA6
PLTP
PRAM1
PRDX2
PRNP
PSEN1
RHEB
RNF32
RPL4
SCARB1
SNCA
SORL1
ST13
TIMM29
TREM2
TYRO3
VLDLR
ZBP1
ZNF558
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Entrez ID |
4846 |
348 |
HPRD ID |
01224 |
00135 |
Ensembl ID |
ENSG00000164867
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ENSG00000130203
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Uniprot IDs |
A0S0A6
P29474
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A0A0S2Z3D5
P02649
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PDB IDs |
1M9J
1M9K
1M9M
1M9Q
1M9R
1NIW
2LL7
2MG5
2N8J
3EAH
3NOS
4D1O
4D1P
5UO8
5UO9
5UOA
5UOB
5UOC
5VVB
5VVC
5VVD
5XOF
6AV6
6AV7
6CIE
6CIF
6NH1
6NH2
6NH3
6NH4
6NH5
6NH6
6NH7
6NH8
6NHF
6POU
6POV
6POW
6POX
6POY
6POZ
6PP0
6PP1
6PP2
6PP3
6PP4
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1B68
1BZ4
1EA8
1GS9
1H7I
1LE2
1LE4
1LPE
1NFN
1NFO
1OEF
1OEG
1OR2
1OR3
2KC3
2KNY
2L7B
6IWB
6NCN
6NCO
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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