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NGFR and NSMCE3
Number of citations of the paper that reports this interaction (PubMedID
14593116
)
44
Data Source:
BioGRID
(affinity chromatography technology, two hybrid, pull down)
NGFR
NSMCE3
Description
nerve growth factor receptor
NSE3 homolog, SMC5-SMC6 complex component
Image
GO Annotations
Cellular Component
Extracellular Region
Nucleoplasm
Endosome
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
Cell Surface
Postsynaptic Density
Integral Component Of Membrane
Growth Cone
Dendritic Spine
Perikaryon
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Cytoplasm
Smc5-Smc6 Complex
Molecular Function
Amyloid-beta Binding
Transmembrane Signaling Receptor Activity
Death Receptor Activity
Protein Binding
Calmodulin Binding
Coreceptor Activity
Small GTPase Binding
Ubiquitin Protein Ligase Binding
Signaling Receptor Activity
Neurotrophin Binding
Nerve Growth Factor Binding
Protein Binding
Protein Dimerization Activity
Biological Process
Cellular Glucose Homeostasis
Intracellular Protein Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Rho Protein Signal Transduction
Axon Guidance
Central Nervous System Development
Detection Of Temperature Stimulus
Nerve Development
Negative Regulation Of Cell Migration
Hair Follicle Morphogenesis
Circadian Regulation Of Gene Expression
Dorsal Aorta Development
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Odontogenesis Of Dentin-containing Tooth
Glucose Homeostasis
Positive Regulation Of Fibroblast Proliferation
Neuron Apoptotic Process
Negative Regulation Of Hair Follicle Development
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Cellular Response To Amyloid-beta
Positive Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
DNA Repair
DNA Recombination
Positive Regulation Of Protein Ubiquitination
Cellular Response To UV
Regulation Of Growth
Cellular Response To Radiation
Cellular Response To Hydroxyurea
Pathways
Axonal growth inhibition (RHOA activation)
NRAGE signals death through JNK
p75NTR negatively regulates cell cycle via SC1
Ceramide signalling
Regulated proteolysis of p75NTR
NFG and proNGF binds to p75NTR
NADE modulates death signalling
NRIF signals cell death from the nucleus
NRIF signals cell death from the nucleus
p75NTR recruits signalling complexes
p75NTR recruits signalling complexes
NF-kB is activated and signals survival
Axonal growth stimulation
SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS
Immune reponse to smallpox (secreted IL-2) (
22610502
)
Lower body strength (
27325353
)
Mean spheric corpuscular volume (
32888494
)
Prostate cancer (
23535732
)
Interacting Genes
51 interacting genes:
ANXA7
APP
BEX1
BEX3
BNIP3L
CAV1
CD80
CDKN1A
COL6A3
EGR1
FSCN1
GRB2
H2AX
IL2
KIDINS220
LINGO1
MAG
MAGED1
MAGEH1
MAPK1
MAPK3
MDM2
NDN
NFKBIB
NGF
NSMCE3
NTF4
NTRK1
NTRK2
NTRK3
PRKACB
PTPN13
RCC1
RIPK2
RPN2
RTN4R
SHC1
SMN1
SORT1
STMN2
TK1
TP53
TRA2B
TRADD
TRAF2
TRAF4
TRAF6
TRIM37
TTR
UFD1
ZNF274
4 interacting genes:
E2F1
NGFR
NSMCE1
TRIM28
Entrez ID
4804
56160
HPRD ID
01197
10503
Ensembl ID
ENSG00000064300
ENSG00000185115
Uniprot IDs
P08138
Q96MG7
PDB IDs
2N80
2N83
2N97
3EWV
5ZGG
5HVQ
5WY5
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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