NFYC and STOX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NFYC	STOX1
Description		nuclear transcription factor Y subunit gamma	storkhead box 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cell Cortex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Protein Folding Positive Regulation Of Transcription By RNA Polymerase II	Cell Cycle Positive Regulation Of Cell Population Proliferation Regulation Of Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Mitochondrion Organization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Transcription By RNA Polymerase II Inner Ear Development Positive Regulation Of Epithelial Cell Proliferation Cell Division Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Protein Kinase B Signaling Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Nitrosative Stress Regulation Of Mitochondrial DNA Metabolic Process Regulation Of Response To Oxidative Stress Positive Regulation Of Cyclin-dependent Protein Kinase Activity Positive Regulation Of Otic Vesicle Morphogenesis
Pathways		PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Adult body size ( 32376654) Airway obstruction (FEV1/FVC<70%) in never smokers ( 30845926) Airway obstruction (FEV1/FVC<lower limit of normal) in never smokers ( 30845926) Depressive and manic episodes in bipolar disorder ( 26297903) Platelet count ( 21507922) Refractive error ( 32231278)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		69 interacting genes: ADGRF5 ADNP2 APOL4 ARID2 ATF6 ATF6B BDH2 BICRA BICRAL CEP76 CIART CIC CRX CSN2 CXorf38 DR1 DST ELF1 FAM168A GAPDH HGS HIVEP1 HSFY1 HSFY2 JAK1 JUN KLF11 KLF15 KLHDC7B LIN54 LMO4 MYC NFYA NFYB NUTM2F OSTF1 PAX4 PAX5 PAX6 POGZ POU3F2 POU6F1 POU6F2 PRR20A PRR20B PRR20C PRR20D PRR20E RAD52 SAE1 SMAD2 SMAD3 SMAP1 SNX2 SP1 SP2 SP4 SREBF2 STOX1 TAF11 TAF12 TAF6 TBP UBXN7 USF3 ZDHHC17 ZMYM6 ZNF34 ZSCAN1	7 interacting genes: ADARB1 BANP GCLM GORASP2 NFYC POU2F1 ROR2
Entrez ID		4802	219736
HPRD ID		05633	18579
Ensembl ID		ENSG00000066136	ENSG00000165730
Uniprot IDs		Q13952	Q6ZVD7
PDB IDs		1N1J 4AWL 4CSR 6QMP 6QMQ 6QMS
Enriched GO Terms of Interacting Partners?
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