NFX1 and RANBP2

Number of citations of the paper that reports this interaction (PubMedID 31375530)
9

Data Source:
BioGRID (fluorescent resonance energy transfer)

		NFX1	RANBP2
Description		nuclear transcription factor, X-box binding 1	RAN binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane	Nuclear Envelope Annulate Lamellae Nuclear Pore Nucleoplasm Cytoplasm Mitochondrion Cytosol Membrane Nuclear Membrane Nuclear Inclusion Body Intracellular Membrane-bounded Organelle Nuclear Pore Cytoplasmic Filaments Nuclear Pore Nuclear Basket Cytoplasmic Periphery Of The Nuclear Pore Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity GTPase Activator Activity Protein Binding Cyclosporin A Binding SUMO Transferase Activity Small GTPase Binding Protein-containing Complex Binding Metal Ion Binding SUMO Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Inflammatory Response Protein Ubiquitination Negative Regulation Of MHC Class II Biosynthetic Process Protein Autoubiquitination	Protein Peptidyl-prolyl Isomerization Response To Amphetamine Regulation Of Gluconeogenesis Protein Folding NLS-bearing Protein Import Into Nucleus Protein Sumoylation Positive Regulation Of Glucokinase Activity MRNA Transport Centrosome Localization
Pathways			ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events EML4 and NUDC in mitotic spindle formation Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Fasting glucose ( 34059833)	Attention deficit hyperactivity disorder ( 29325848) Beard thickness ( 26926045) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)
Interacting Genes		12 interacting genes: CDKN2A ELAVL4 MAML3 NUP153 NUP214 NUP62 NUP98 PPP1R16B RANBP2 SIGMAR1 UBC UBE2N	39 interacting genes: AKAP13 ARID4B CALM1 CDCA8 CUL1 FHOD1 GCC2 HDAC4 IFT140 IPO5 KPNA1 KPNA2 KPNB1 LRPAP1 MAP2K7 MDM2 MYBPC2 NFX1 NUP62 NXF1 OPN1LW OPN1MW PDLIM3 PRKN PTEN RAN RANGAP1 SENP1 SP100 SUMO1 SUMO2 TAF1 TNPO1 TOP2B UBE2I UBTD1 WAS XPO1 XPOT
Entrez ID		4799	5903
HPRD ID		11936	03111
Ensembl ID		ENSG00000086102	ENSG00000153201
Uniprot IDs		Q12986	P49792
PDB IDs			1RRP 1XKE 1Z5S 2LAS 3UIN 3UIO 3UIP 4GA0 4I9Y 4L6E 4LQW 5CLL 5CLQ
Enriched GO Terms of Interacting Partners?
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