NDUFAB1 and TOX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NDUFAB1	TOX2
Description		NADH:ubiquinone oxidoreductase subunit AB1	TOX high mobility group box family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Mitochondrial Membrane	Nucleus Nucleoplasm
	Molecular Function	Acyl Binding Acyl Carrier Activity Fatty Acid Binding Calcium Ion Binding Protein Binding	Transcription Coactivator Activity Chromatin DNA Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Fatty Acid Biosynthetic Process Protein Lipoylation Mitochondrial Respiratory Chain Complex I Assembly	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Glyoxylate metabolism and glycine degradation Respiratory electron transport Complex I biogenesis Mitochondrial Fatty Acid Beta-Oxidation
Drugs		NADH
Diseases
GWAS		Bipolar disorder ( 17554300)	Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Colorectal cancer ( 30529582) Conduct disorder (symptom count) ( 20585324) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) White blood cell count ( 32888494)
Interacting Genes		35 interacting genes: ACTN3 BBC3 BEX5 CCDC24 CNTF EIF3B ERBB3 FEM1A FHL3 FNDC3B HINFP KCTD9 LMO2 LNX1 MBLAC1 MORN3 MRPL23 NOXA1 NRF1 NT5C3A NTAQ1 OIP5 POP5 PPP1R16A PSMC3 RBM18 SLIRP SMYD3 THAP1 TLX3 TOX2 VAC14 ZNF19 ZNF410 ZNF829	24 interacting genes: ANKS1A APP CENPP CSTF2T ENKD1 HCK HOMER3 HSF2BP HSFY1 HSFY2 LGALS4 MFHAS1 NDUFAB1 P4HA3 PHF1 RIBC1 SPG21 TCEA2 TEKT4 TEKT5 TLX3 UNC5CL YPEL3 ZNF461
Entrez ID		4706	84969
HPRD ID		11951	12734
Ensembl ID		ENSG00000004779	ENSG00000124191
Uniprot IDs		O14561	Q96NM4
PDB IDs		2DNW 5OOL 5OOM 5XTB 5XTC 5XTD 5XTH 5XTI 6ODD 7A5H 7A5J
Enriched GO Terms of Interacting Partners?
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