NDUFA3 and SLC7A8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NDUFA3	SLC7A8
Description		NADH:ubiquinone oxidoreductase subunit A3	solute carrier family 7 member 8
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Microvillus Membrane
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Protein Binding Organic Cation Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity Glycine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity Peptide Antigen Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly	Amino Acid Transmembrane Transport Amino Acid Transport Response To Toxic Substance Organic Cation Transport Neutral Amino Acid Transport Glycine Transport Leucine Transport Tryptophan Transport Valine Transport Proline Transmembrane Transport Metal Ion Homeostasis Thyroid Hormone Transport Amino Acid Import Across Plasma Membrane Leucine Import Across Plasma Membrane Transport Across Blood-brain Barrier Toxin Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane
Pathways		Respiratory electron transport Complex I biogenesis	Basigin interactions Amino acid transport across the plasma membrane
Drugs		NADH	Phenylalanine Alanine
Diseases
GWAS
Interacting Genes		14 interacting genes: CRB3 EBP ERG28 GOLT1A MMGT1 MUC1 SLC7A8 TLCD4 TM4SF19 TMEM101 TMEM14B TMEM205 TMEM242 TMX2	26 interacting genes: ABHD16A AGPAT4 AQP6 COMT DERL1 FXYD6-FXYD2 MFF MFSD3 NDUFA3 NINJ2 REEP4 SIGLEC5 SLC25A46 SLC30A2 SLC3A1 SLC3A2 SMPD2 SNORC SYCE1L SYNJ2BP TMEM14B TMEM208 TMEM60 TMEM65 YIPF1 YIPF6
Entrez ID		4696	23428
HPRD ID		04830	11971
Ensembl ID		ENSG00000170906	ENSG00000092068
Uniprot IDs		O95167 Q6FGG4	Q53EM9 Q9UHI5
PDB IDs		5XTC 5XTD 5XTH 5XTI	7CMH 7CMI
Enriched GO Terms of Interacting Partners?
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