NDN and MKRN2

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid, two hybrid)

		NDN	MKRN2
Description		necdin, MAGE family member	makorin ring finger protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Cytosol Protein-containing Complex Cell Projection Perikaryon
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Gamma-tubulin Binding Promoter-specific Chromatin Binding	RNA Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Respiratory System Process Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Population Proliferation Glial Cell Migration Post-embryonic Development Sensory Perception Of Pain Regulation Of Growth Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting Positive Regulation Of Protein Deacetylation	Biological_process Protein Ubiquitination
Pathways		Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Depressive symptoms (SSRI exposure interaction) ( 25649181) HDL cholesterol levels ( 32203549) Parkinson's disease (age of onset) ( 33884653) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)	Hip index ( 34021172) Monocyte percentage of white cells ( 32888494) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PALS2 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B	15 interacting genes: C1orf109 CLK1 EIF3F IGF2BP3 MRPS25 NDN PALS2 PDLIM2 RACK1 RBCK1 RELA UBE2D1 UBE2D4 UBE2K UBE2L3
Entrez ID		4692	23609
HPRD ID		03667	09761
Ensembl ID		ENSG00000182636	ENSG00000075975
Uniprot IDs		Q99608 X5D982	Q9H000
PDB IDs
Enriched GO Terms of Interacting Partners?
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