NAP1L1 and TPX2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NAP1L1	TPX2
Description		nucleosome assembly protein 1 like 1	TPX2 microtubule nucleation factor
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Membrane Melanosome	Spindle Pole Nucleus Nucleoplasm Spindle Cytosol Nuclear Microtubule Microtubule Cytoskeleton Axon Hillock Intercellular Bridge Mitotic Spindle
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Histone Binding	Protein Binding Microtubule Binding Protein Kinase Binding Protein Kinase Activator Activity Importin-alpha Family Protein Binding
	Biological Process	DNA Replication Nucleosome Assembly Positive Regulation Of Cell Population Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Neural Precursor Cell Proliferation	Mitotic Cell Cycle Apoptotic Process Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Activation Of Protein Kinase Activity Cell Division Regulation Of Mitotic Spindle Organization Mitotic Spindle Assembly
Pathways			Regulation of TP53 Activity through Phosphorylation AURKA Activation by TPX2
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)	Brain morphology (MOSTest) ( 32665545) Immature fraction of reticulocytes ( 32888494) Mean reticulocyte volume ( 32888494) Monocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Prudent dietary pattern ( 28644415)
Interacting Genes		37 interacting genes: ANKRD23 C1QTNF9 CDK3 CES2 CHORDC1 CREBBP CSNK2A1 CSNK2B DLST EP300 ERCC6 FSD1 GAS2L2 H1-1 H3C1 H4C1 HBA1 HMGB2 HSPB1 KCNMB3 LINC01554 MED10 MTIF2 MTNR1A NAP1L2 NR2F6 OGT POT1 RPL23A RPS15 SP1 SUMO2 TERF1 TP53 TPX2 UBQLN2 ZDHHC17	8 interacting genes: AURKA CDK6 GOLGA2 HMMR NAP1L1 SIAH2 SUMO2 THAP11
Entrez ID		4673	22974
HPRD ID		01248	05802
Ensembl ID		ENSG00000187109	ENSG00000088325
Uniprot IDs		A0A024RBB7 B7Z2V4 F5H4R6 F8W543 P55209 Q9H2B0	Q643R0 Q9ULW0
PDB IDs			1OL5 3E5A 3HA6 4C3P 5LXM 6BJC 6VPG 6VPH 6VPI 6VPJ 6VPL 6VPM 6XKA
Enriched GO Terms of Interacting Partners?
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