MYBPC2 and AMOT

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		MYBPC2	AMOT
Description		myosin binding protein C2	angiomotin
Image
GO Annotations	Cellular Component	Cytosol Myosin Filament	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle	Protein Binding Signaling Receptor Activity Angiostatin Binding
	Biological Process	Muscle Contraction Cell Adhesion	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Primary biliary cholangitis ( 26394269)
Interacting Genes		31 interacting genes: ACTN2 AMOT AOC3 CCT6A CMYA5 COL12A1 DST DYSF FLNB FLNC FSD2 GABARAP GAS7 HSPA1B ITGB5 MAD2L2 MSN MYBPC1 MYBPH MYH8 MYOM2 NF2 PCDH12 PDE4DIP RANBP2 SDCBP SGCG TRIM63 TRIP11 TTN TULP3	57 interacting genes: ACTA1 AMOTL2 AP1M1 APP AQP1 AXIN2 C1orf216 CAPN3 DISC1 FHL2 HOXA1 HPCAL1 KIAA1328 KRT14 KRT15 KRT16 KRT19 KRT24 KRT27 KRT31 KRT34 KRT36 KRT75 LCE1D LMNB2 LMO4 LURAP1 LZTS1 MAGEA4 MAGI1 MAPK3 MED4 MEOX2 MIS18A MYBPC1 MYBPC2 MYOM3 NEDD4 NEDD4L NTAQ1 NUFIP2 PBLD PIK3C2A PIN1 PLG PRKAA2 PTEN PTPA RBM48 SEPTIN1 SLIRP SMC1A SNAPC5 SOCS6 THRA TTN UNC119
Entrez ID		4606	154796
HPRD ID		01184	02327
Ensembl ID		ENSG00000086967	ENSG00000126016
Uniprot IDs		A0A140VJQ0 Q14324	Q4VCS5
PDB IDs		2E7C 2EDK 2EDN	6JJX
Enriched GO Terms of Interacting Partners?
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