MTX1 and CLN8

Number of citations of the paper that reports this interaction (PubMedID 23142642)
7

Data Source:
BioGRID (two hybrid)

		MTX1	CLN8
Description		metaxin 1	CLN8 transmembrane ER and ERGIC protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	SAM Complex Cytoplasm Integral Component Of Membrane MIB Complex	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Presynapse
	Molecular Function	Molecular_function Protein Binding	Protein Binding Ceramide Binding
	Biological Process	Mitochondrion Organization Inner Mitochondrial Membrane Organization Lactation Protein Transport	Age-dependent Response To Oxidative Stress Phospholipid Metabolic Process Ceramide Metabolic Process Lipid Transport Mitochondrial Membrane Organization Lysosome Organization Nervous System Development Visual Perception Adult Walking Behavior Cholesterol Metabolic Process Associative Learning Regulation Of Cell Size Lipid Biosynthetic Process Somatic Motor Neuron Differentiation Protein Catabolic Process Social Behavior Negative Regulation Of Apoptotic Process Cellular Protein Catabolic Process Photoreceptor Cell Maintenance Negative Regulation Of Proteolysis Ceramide Biosynthetic Process Musculoskeletal Movement Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Glutamate Reuptake Lipid Homeostasis Retina Development In Camera-type Eye Neurofilament Cytoskeleton Organization
Pathways		Mitochondrial protein import Cristae formation RAC2 GTPase cycle
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462 31451708) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric cancer ( 26098866) General risk tolerance (MTAG) ( 30643258) Gout ( 33832965) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Red blood cell count ( 32888494 27863252) Renal function-related traits (BUN) ( 22797727) Serum cancer antigen 15.3 levels ( 31666285) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528) Urea levels ( 28270201)	Eye morphology ( 29921221) Gaucher disease severity ( 22388998) Systolic blood pressure ( 30224653) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		3 interacting genes: CLN8 MTX2 TOMM40	30 interacting genes: ARL6IP5 BNIP3 BNIP3L CD9 CYB5B ERG28 FZD7 GABARAPL2 GPM6B MTX1 NDRG2 PDIA6 PLP1 PLP2 PTPRN RRP15 RTN4 SELENOK SPCS2 STX8 TMEM107 TMEM11 TMEM128 TMEM134 TMEM147 TMEM14A TUBB4A UBC YIPF6 ZUP1
Entrez ID		4580	2055
HPRD ID		11861	06383
Ensembl ID		ENSG00000173171	ENSG00000182372
Uniprot IDs		Q13505	A0A024QZ57 Q9UBY8
PDB IDs
Enriched GO Terms of Interacting Partners?
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