MLLT1 and AFF4

Number of citations of the paper that reports this interaction (PubMedID 26344197)
178

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (two hybrid)

		MLLT1	AFF4
Description		MLLT1 super elongation complex subunit	AF4/FMR2 family member 4
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytosol Transcription Elongation Factor Complex	Fibrillar Center Nucleoplasm Transcription Elongation Factor Complex Super Elongation Complex Transcriptionally Active Chromatin
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Protein Kinase Activity	Spermatid Development Regulation Of Gene Expression
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288)	Asthma ( 31619474) Body shape index ( 34021172) Estimated glomerular filtration rate ( 31152163) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		14 interacting genes: AFF1 AFF4 ALKBH4 ARID1A BMI1 CBX8 FXR1 H1-5 H3-4 MLLT10 NFIX PAF1 WDR5 YIF1A	11 interacting genes: AP2B1 CCNT1 CDK9 ELL2 GOLGA2 LRRK2 MLLT1 MTUS2 SIAH1 SPP1 TRAF2
Entrez ID		4298	27125
HPRD ID		15933	09187
Ensembl ID		ENSG00000130382	ENSG00000072364
Uniprot IDs		Q03111	Q9UHB7
PDB IDs		5J9S 6HPW 6HPX 6HPY 6HPZ 6HQ0 6HT0 6HT1 6T1I 6T1J 6T1L 6T1M 6T1N 6T1O 7B0T 7B10	4IMY 4OGR 4OR5 5JW9 5L1Z 6CYT 6K7P 6KN5 6R80
Enriched GO Terms of Interacting Partners?
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